Publications by authors named "Kelvin Gotama"

Background: The demographic, clinical, and angiographic features of ruptured aneurysms compared to unruptured cerebral aneurysms in Indonesia are still limited. This study aims to determine risk factors for rupture according to clinical patterns and morphological features in the Indonesian population.

Method: We retrospectively reviewed all cerebral aneurysm registries at the largest comprehensive stroke center in Indonesia from January 2019 to January 2022.

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Article Synopsis
  • Pericytes, which are mural cells in the neurovascular unit, help maintain the blood-brain barrier and cerebral blood flow, and their role in dementia, particularly in the hippocampus, is not well understood.
  • A study of 90 post-mortem brains revealed that pericyte densities were significantly lower (25-40%) in patients with post-stroke dementia, vascular dementia, and Alzheimer's disease when compared to controls, especially in the cornu ammonis (CA) 1 region.
  • Mouse models showed a 60% loss of pericytes with chronic hypoperfusion, but engaging these mice in an enriched environment helped reduce pericyte loss and associated hippocampal atrophy, suggesting that a vascular
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Introduction: The anterior communicating artery (ACoA) aneurysm, the most frequent cerebral aneurysm to rupture, carries a significant clinical burden, yet the factors influencing its rupture are limited in Indonesia. This study aims to determine the clinical and morphological features associated with ruptured ACoA compared to non-AcoA aneurysms among Indonesians.

Patients And Methods: We retrospectively reviewed our center's aneurysm patient registry from January 2019 to December 2022, and compared the clinical and morphological features between ruptured ACoA aneurysms and ruptured aneurysms elsewhere with univariate and multivariate analyses.

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Background: Length of stay (LOS) is an important indicator of the optimization of health services and hospital financing efficiency in aneurysmal subarachnoid hemorrhage (aSAH) patients. The purpose of this study was to develop a scoring model to predict the LOS of patients with aSAH.

Method: A clinical scoring was developed based on retrospectively collected data from the cerebral aneurysm registry of the National Brain Center Hospital, Jakarta, from January 2019 to June 2022.

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