Publications by Kelsi M Wells

Publications by authors named "Kelsi M Wells"

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Diminished Ost3-dependent N-glycosylation of the BiP nucleotide exchange factor Sil1 is an adaptive response to reductive ER stress.

Kofi L P Stevens Amy L Black Kelsi M Wells K Y Benjamin Yeo Robert F L Steuart

Proc Natl Acad Sci U S A

November 2017

BiP (Kar2 in yeast) is an essential Hsp70 chaperone and master regulator of endoplasmic reticulum (ER) function. BiP's activity is regulated by its intrinsic ATPase activity that can be stimulated by two different nucleotide exchange factors, Sil1 and Lhs1. Both Sil1 and Lhs1 are glycoproteins, but how N-glycosylation regulates their function is not known.

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