Publications by authors named "Kelsey I Ricci"
Article Synopsis
- The study aimed to analyze the characteristics of F-FDG PET imaging in pediatric diffuse intrinsic pontine glioma (DIPG) and how they relate to MRI metrics and patient survival outcomes.
- Baseline brain scans from 33 children were evaluated, focusing on various imaging metrics including PET and MRI histogram parameters, but no significant association was found between PET metrics and progression-free survival (PFS).
- However, a notable correlation emerged between higher MRI ADC skewness and shorter PFS, suggesting that certain MR metrics might better predict survival outcomes than PET imaging in these patients.
Background: Diffuse intrinsic pontine glioma (DIPG) is associated with poor survival regardless of therapy. We used volumetric apparent diffusion coefficient (ADC) histogram metrics to determine associations with progression-free survival (PFS) and overall survival (OS) at baseline and after radiation therapy (RT).
Methods: Baseline and post-RT quantitative ADC histograms were generated from fluid-attenuated inversion recovery (FLAIR) images and enhancement regions of interest.
Rationale And Objectives: Magnetic resonance diffusion imaging can characterize physiologic characteristics of pediatric brain tumors used to assess therapy response. The purpose of this study was to assess the variability of the apparent diffusion coefficient (ADC) along z-axis of scanners in the multicenter Pediatric Brain Tumor Consortium (PBTC).
Materials And Methods: Ice-water diffusion phantoms for each PBTC site were distributed with a specific diffusion imaging protocol.