Publications by authors named "Kellylynn E Wheeler"
Effects of hyperthermia and boric acid on skeletal development in rat embryos.
Birth Defects Res B Dev Reprod Toxicol
June 2005
Article Synopsis
- The study investigates the effects of boric acid (BA) and hyperthermia on the development of skeletal defects in rat offspring when combined during pregnancy.
- Pregnant rats were treated with varying doses of BA and different temperatures of hyperthermia on gestational day 10, and their litters were analyzed for defects in skeletal structure on postnatal days 1 and 3.
- Results demonstrated that both treatments increased the incidence of skeletal defects, with the combination of BA and hyperthermia leading to even more significant issues, particularly in vertebral segmentation and total vertebrae count.