National estimates of insulin-related hypoglycemia and errors leading to emergency department visits and hospitalizations.

Importance: Detailed, nationally representative data describing high-risk populations and circumstances involved in insulin-related hypoglycemia and errors (IHEs) can inform approaches to individualizing glycemic targets.

Objective: To describe the US burden, rates, and characteristics of emergency department (ED) visits and emergency hospitalizations for IHEs.

Design, Setting, And Participants: Nationally representative public health surveillance of adverse drug events among insulin-treated patients seeking ED care (National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project) and a national household survey of insulin use (the National Health Interview Survey) were used to obtain data from January 1, 2007, through December 31, 2011.

National surveillance of emergency department visits for outpatient adverse drug events in children and adolescents.

Objective: To describe the national scope and magnitude of outpatient adverse drug events (ADEs) that lead to emergency department (ED) visits in children and adolescents.

Study Design: To conduct an active surveillance of patients 18 years of age or younger who came to EDs with ADEs from Jan 1, 2004, to Dec 31, 2005, through a nationally representative, stratified probability sample of 63 US hospitals with EDs. The main outcome measures were national estimates of the number, type, patient demographics, and clinical characteristics of ADEs.

Evaluation and overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES).

Background: Adverse drug events (ADEs) are an important cause of patient injury. Although most medications are prescribed and used in the outpatient setting, prevention efforts focus on the inpatient setting, partly because of limited data on outpatient events. We describe and evaluate a new system for surveillance of outpatient ADEs treated in hospital emergency departments (EDs).

National surveillance of emergency department visits for outpatient adverse drug events.

Context: Adverse drug events are common and often preventable causes of medical injuries. However, timely, nationally representative information on outpatient adverse drug events is limited.

Objective: To describe the frequency and characteristics of adverse drug events that lead to emergency department visits in the United States.

Emergency department visits for outpatient adverse drug events: demonstration for a national surveillance system.

Study Objective: This project demonstrates the operational feasibility and epidemiologic usefulness of modifying a national injury surveillance system for active surveillance of outpatient adverse drug events treated in hospital emergency departments (EDs).

Methods: Coders were trained to identify and report physician-documented adverse drug events in 9 of 64 National Electronic Injury Surveillance System-All Injury Program hospital EDs (occurring July 17, 2002, to September 30, 2002). Feasibility was measured by timeliness and completeness of adverse drug event reporting.