Photoactivated riboflavin treatment of infectious keratitis using collagen cross-linking technology.

Purpose: To evaluate riboflavin/ultraviolet-A (UVA) as an adjunct treatment for infectious keratitis.

Methods: This prospective, dual-center, interventional case series included cases of infectious keratitis that were treated by instilling riboflavin 0.1% solution for 30 minutes to saturate the cornea, followed by exposure to 365-nm UVA light (3 mW/cm(2)) for 15 to 45 minutes, with continued instillation of riboflavin.

Comparison of manual and automated endothelial cell density analysis in normal eyes and DSEK eyes.

Purpose: To compare automated endothelial cell density analysis with manual cell detection methods with 3 imaging devices.

Methods: In this prospective study, the corneal endothelium of 54 Descemet stripping endothelial keratoplasty (DSEK) eyes and 28 normal eyes was analyzed with a Nidek Confoscan 4 confocal microscope using a 20× noncontact lens and with Tomey EM-3000 and Konan Noncon Robo SP-8800 specular microscopes. Testing order was randomized.

Prospective study of visual outcomes and endothelial survival with Descemet membrane automated endothelial keratoplasty.

Purpose: To evaluate vision and endothelial cell survival in an initial Descemet membrane automated endothelial keratoplasty (DMAEK) series.

Methods: This was a prospective nonrandomized study of an initial consecutive series of 40 DMAEK cases, performed with or without concomitant phacoemulsification and intraocular lens implantation. The graft was dissected with a microkeratome.

Descemet's stripping endothelial keratoplasty five-year graft survival and endothelial cell loss.

Purpose: To assess 5-year Descemet's stripping endothelial keratoplasty (DSEK) graft survival and endothelial cell loss in the surviving grafts.

Design: Retrospective, interventional case series.

Participants: One hundred sixty-five eyes of 149 patients treated with primary DSEK.

Rate and risk factors for cataract formation and extraction after Descemet stripping endothelial keratoplasty.

Purpose: To assess the rate and risk factors for cataract formation and extraction after Descemet stripping endothelial keratoplasty (DSEK).

Methods: An initial, consecutive series of 1050 primary DSEK procedures was reviewed to identify eyes that remained phakic. Only the first-treated eye of each patient was included; 60 eyes qualified.

Descemet's membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival.

Purpose: To describe Descemet's membrane endothelial keratoplasty (DMEK) techniques, perioperative challenges, management, and visual and refractive outcomes.

Design: Prospective, multicenter, consecutive case series.

Participants: Sixty eyes of 56 patients with Fuchs' endothelial dystrophy, pseudophakic bullous keratopathy, or failed previous graft.