Ototoxicity: Visualized in Concept Maps.

Ototoxicity refers to the damage to structures and function of the auditory-vestibular system caused by exogenous agents such as pharmaceuticals, chemicals, and ionizing radiation. There are many potentially ototoxic substances. For example, depending on how ototoxicity is defined, there are 200 to 600 medications that can cause damage to hearing and/or balance.

Development of the Warfighter's Hearing Health Instructional (WHHIP) Primer App.

The Warfighter's Hearing Health Instructional Primer (WHHIP) is a supplemental tool for military hearing conservation programs (MHCPs) and can be accessed by the warfighter on his/her own personal mobile phone. A gap was identified for a supplement to MHCPs that is easily accessible by warfighters to improve hearing health knowledge. The WHHIP aims to instruct the warfighter in best hearing health practices.

The effects of energetic and informational masking on The Words-in-Noise Test (WIN).

Background: In certain masking paradigms, the masker can have two components, energetic and informational. Energetic masking is the traditional peripheral masking, whereas informational masking involves confusions (uncertainty) between the signal and masker that originate more centrally in the auditory system. Sperry et al (1997) used Northwestern University Auditory Test No.

The Revised Speech Perception in Noise Test (R-SPIN) in a multiple signal-to-noise ratio paradigm.

Background: The Revised Speech Perception in Noise Test (R-SPIN; Bilger, 1984b) is composed of 200 target words distributed as the last words in 200 low-predictability (LP) and 200 high-predictability (HP) sentences. Four list pairs, each consisting of two 50-sentence lists, were constructed with the target word in a LP and HP sentence. Traditionally the R-SPIN is presented at a signal-to-noise ratio (SNR, S/N) of 8 dB with the listener task to repeat the last word in the sentence.

The Words-in-Noise Test (WIN), list 3: a practice list.

Background: The Words-in-Noise Test (WIN) was developed as an instrument to quantify the ability of listeners to understand monosyllabic words in background noise using multitalker babble (Wilson, 2003). The 50% point, which is calculated with the Spearman-Kärber equation (Finney, 1952), is used as the evaluative metric with the WIN materials. Initially, the WIN was designed as a 70-word instrument that presented ten unique words at each of seven signal-to-noise ratios from 24 to 0 dB in 4 dB decrements.

Development of the Listening Self-Efficacy Questionnaire (LSEQ).

Objective: Listening self-efficacy refers to the beliefs, or confidence, that listeners have in their capability to successfully listen in specific situations, which may influence audiologic rehabilitation outcomes. The objective of this study was to develop and validate the Listening Self-Efficacy Questionnaire (LSEQ), which quantifies listening self-efficacy in a variety of situations where the goal of the listener is to understand speech.

Study Sample: Older listeners with hearing loss (N = 169) participated in the study.

Effects of low-frequency biasing on spontaneous otoacoustic emissions: amplitude modulation.

The dynamic effects of low-frequency biasing on spontaneous otoacoustic emissions (SOAEs) were studied in human subjects under various signal conditions. Results showed a combined suppression and modulation of the SOAE amplitudes at high bias tone levels. Ear-canal acoustic spectra demonstrated a reduction in SOAE amplitude and growths of sidebands while increasing the bias tone level.

Effect of MRI coregistration on serial short-term brain volume changes in multiple sclerosis.

Objective: To test the effect of serial magnetic resonance (MR) coregistration on short-term brain volume changes using different semiautomated and automated brain volume techniques in patients with relapsing-remitting (RR) multiple sclerosis (MS). Coregistration is frequently used to increase precision in serial MR imaging (MRI) analyses. However, the effect of coregistration on measurement of whole brain volume changes from serial scans in the short term has not been tested in MS patients.