Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis.

Background: Conflicting results about the prognostic relevance of signet ring cell histology in gastric cancer have been reported. We aimed to perform a meta-analysis focusing on the clinicopathological features and prognosis of this subgroup of cancer compared with other histologies.

Methods: A systematic literature search in the PubMed database was conducted, including all publications up to 1 October 2021.

Internal Carotid Artery Stenosis and Collateral Recruitment in Stroke Patients.

Purpose: Leptomeningeal collaterals improve outcome in stroke patients. There is great individual variability in their extent. Internal carotid artery (ICA) stenosis may lead to more extensive recruitment of leptomeningeal collaterals.

The disease recurrence rate after the canal wall up or canal wall down technique in adults.

Objectives/hypothesis: To review which type of cholesteatoma surgery, canal wall up (CWU) or canal wall down (CWD), provides the lowest risk for residual and/or recurrent disease in adults with primary acquired cholesteatoma.

Data Sources: PubMed, Embase, CINAHL, the Cochrane Library, Scopus and Web of Science.

Study Design: We selected articles comparing CWU with CWD, reporting on disease recidivism (combined residual and recurrent disease) or independent residual or disease recurrence rates.