Hypoxemic versus normoxemic reperfusion in a large animal model of severe ischemia-reperfusion injury.

Background: Prior studies have suggested a significant benefit of using deliberate hypoxemia to reperfuse ischemic tissue beds, primarily by reducing free radical injury. We sought to examine the effects of a hypoxemic reperfusion strategy in a large animal model of severe truncal ischemia.

Materials And Methods: Adult swine were subjected to 30 min of supraceliac aortic occlusion and randomized to two groups: normoxemia group (n = 9), with resuscitation at a pO2 >100 mmHg or hypoxemia group (n = 10), with initial resuscitation at a pO2 of 30-50.

Improved rates of colorectal cancer screening in an equal access population.

Background: National colorectal cancer (CRC) screening averages 50% to 60%. We aimed to identify screening prevalence in select Department of Defense (DOD) beneficiaries with equal access to care.

Methods: December 2007 cross-sectional data of patients over 50 years of age included patient demographics, screening modality, and compliance.