Current and Approaches to Uncovering Mechanisms of Neurological Dysfunction after Traumatic Brain Injury.

Traumatic brain injury often leads to progressive alterations at the molecular to circuit levels resulting in epilepsy and memory impairments. and models have provided a powerful platform for investigating the multimodal alteration after trauma. Recent analyses using voltage sensitive dye imaging, optogenetics, and glutamate uncaging have revealed circuit abnormalities following brain injury.