Publications by authors named "Kelly A Pierce"
Emerg Infect Dis
March 2023
Article Synopsis
- Schools in the U.S. closed in early 2020 due to COVID-19 and struggled to implement consistent testing to minimize transmission when reopening.*
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- The study introduces a test allocation method that tailors testing levels to different campuses, aiming to reduce infection rates and disparities among schools within diverse districts.*
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- By applying this optimized method in a Texas school district, the researchers demonstrated a significant reduction in infection rate disparities, creating a model for future proactive testing against COVID-19 and other pathogens.*
Article Synopsis
- Clinicians are increasingly using next-generation sequencing (NGS) for genomic tests due to its accuracy, but rare errors can occur that could lead to incorrect patient management.
- An alternative to Sanger sequencing for verifying NGS results is a software-assisted manual review, which was evaluated against Sanger for over 15,000 samples.
- The study found that this manual review method achieved similar accuracy to Sanger confirmation, particularly for problematic variants, suggesting it could be a viable option for ensuring high-quality NGS results.
