This study investigates how both short-term (acute) and long-term (chronic) alcohol exposure affects the structure of neurons in the brain, specifically looking at neurite density.
Using advanced imaging techniques, including neurite orientation dispersion and density imaging (NODDI), researchers compared effects in healthy social drinkers versus individuals with alcohol use disorder.
The findings reveal significant differences in various parameters related to white matter in the brain, particularly in the corpus callosum, suggesting that even short-term alcohol infusion can alter brain properties that were previously thought to be unaffected by immediate changes in substance intake.