The risk of necrotizing enterocolitis after indomethacin tocolysis.

Background: Postnatal indomethacin is reportedly associated with an increased incidence of necrotizing enterocolitis (NEC) in preterm infants. Because indomethacin readily crosses the placenta, we hypothesized that antenatal indomethacin (AI) would increase the risk for NEC in preterm infants.

Objective: The goal of this study was to explore the association between AI and NEC in preterm infants.