Publications by authors named "Kelliann Fee-Schroeder"
Article Synopsis
- The Mayo-Baylor RIGHT 10K Study focused on using pharmacogenomics to improve drug prescriptions based on genetic information in a large population.
- Researchers sequenced the DNA of over 10,000 participants to identify genetic variations affecting drug responses, and integrated these findings into electronic health records.
- Results showed that 79% of participants had actionable genetic variants affecting their medication, highlighting the need for a proactive approach to personalized medicine in clinical care.
Purpose: The Pharmacogenomics (PGx) Profile Service was a proof-of-concept project to implement PGx in patient care at Mayo Clinic.
Methods: Eighty-two healthy individuals aged 18 and older underwent genotyping of CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, SLCO1B1, HLA-B*58:01, and VKORC1. A PGx pharmacist was involved in ordering, meeting with patients, interpreting, reviewing, and documenting results.
Gaps in nurses' knowledge and application related to genomics exist. This project aimed to develop an accessible genomic education program for oncology nurses. Consequently, the flipped classroom strategy was used.
View Article and Find Full Text PDFPurpose: Hot flashes are a significant source of symptom burden that negatively impacts quality of life (QOL). For women who have contraindications to, or are unwilling to consider, estrogens or antidepressants for bothersome hot flashes, there are limited effective pharmacologic or complementary and alternative medicines.
Methods: This single-arm phase II trial studied the efficacy of S-adenosyl-L-methionine (SAMe) for the treatment of hot flashes.
Purpose: Chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of chemotherapy, needs better effective treatments. Preliminary data support the use of Scrambler therapy, a device which treats pain via noninvasive cutaneous electrostimulation, for the treatment of CIPN. The current manuscript reports data from a pilot trial, performed to investigate the effect of Scrambler therapy for the treatment of established CIPN.
View Article and Find Full Text PDFPurpose: Adherence to guideline-consistent chemotherapy-induced nausea and vomiting (CINV) prophylaxis is suboptimal. The primary aim of this study was to evaluate the magnitude of compliance to institutional guideline-directed antiemetic prophylaxis using a computerized physician order entry system at a single tertiary care institution. A nurse survey was also performed to evaluate how oncology practices, within a cooperative group, managed clinician orders for the prevention of CINV.
View Article and Find Full Text PDFProviding concise, consistent, and individually relevant patient education is critical. At one institution, patients and families attended a chemotherapy education class consisting of an 11-minute DVD and an oncology nurse-facilitated group discussion. Postclass and eight-week follow-up surveys assessing understanding of treatment side effects, self-care management, and confidence in managing side effects were administered.
View Article and Find Full Text PDFPurpose/objectives: To evaluate the most prevalent physical, social, emotional, and spiritual concerns of cancer survivors.
Design: Descriptive, cross-sectional study.
Setting: A matrix (multisite) cancer center in three urban centers in the United States.
Purpose/objectives: To determine which method of delivery of a cancer orientation program contributed to higher levels of satisfaction and lower levels of anxiety for newly diagnosed patients with cancer and each patient's support person.
Design: A randomized study of patients with cancer and caregivers into one of three delivery methods for an orientation program or a control arm.
Setting: A National Cancer Institute-designated comprehensive cancer center in the midwestern United States.