Publications by authors named "Kelli P A Macdonald"
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Synopsis of recent research by authors named "Kelli P A Macdonald"
- Kelli P A MacDonald's recent research focuses primarily on the mechanisms and therapeutic strategies related to graft-versus-host disease (GVHD) and its complications, particularly in the context of hematopoietic stem cell transplantation (HSCT).
- Her studies highlight the role of autophagy in hematopoietic stem cell fitness during transplantation and the regulatory mechanisms of immune cell function in both GVHD and neuroinflammation related to traumatic brain injury.
- MacDonald's findings suggest innovative therapeutic options, such as targeting specific pathways (like ROCK2 and CSF1R), and enhancing regulatory T cell function to mitigate GVHD severity and improve outcomes in transplant models.