Publications by authors named "Kelli M Torsney"
Article Synopsis
- Parkinson's disease (PD) is a neurodegenerative disorder characterized by movement issues and non-motor symptoms, primarily caused by the loss of dopaminergic neurons in the brain.
- Currently, there are no effective treatments to modify the disease, with existing therapies mainly focused on managing symptoms through dopaminergic drugs and some surgical options.
- New research is exploring regenerative cell-based and gene therapies that show promise in early trials, aiming to restore dopamine levels and reduce harmful α-synuclein aggregates, potentially transforming PD management in the near future.
Parkinson's disease (PD) is associated with an increased risk of fragility fracture. FRAX and Qfracture are risk calculators that estimate the 10-year risk of hip and major fractures and guide definitive investigation for osteoporosis using dual X-ray absorptiometry (DEXA) imaging. It is unclear which PD patients should be considered for fracture risk assessment and whether FRAX or Qfracture should be used.
View Article and Find Full Text PDFBone health in Parkinson's disease: a systematic review and meta-analysis.
J Neurol Neurosurg Psychiatry
October 2014
Objective: Parkinson's disease (PD) and osteoporosis are chronic diseases associated with increasing age. Single studies have reported associations between them and the major consequence, namely, increased risk of fractures. The aim of this systematic review and meta-analysis was to evaluate the relationship of PD with osteoporosis, bone mineral density (BMD) and fracture risk.
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