Publications by authors named "Kelli Fasenmyer"
Background: Posttraumatic stress disorder (PTSD) is a stress disorder that develops in only some individuals following a traumatic event. Data suggest that a substantial fraction of women recover after sexual violence. Thus, the investigation of stress and antistress neuropeptides in this sample has the potential to inform the neurochemistry of resilience following trauma.
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- Investigated the link between the Val158Met polymorphism in the COMT gene and its effects on dopamine levels in the prefrontal cortex.
- Previous studies suggested a connection between this genetic variant and D1/D2 receptor binding related to dopaminergic tone, but relied on potentially flawed measures.
- The current study, using amphetamine to measure dopamine release in 31 healthy participants, found no significant relationship between COMT genotype and prefrontal cortical dopamine release or baseline D2/3 receptor binding.