Publications by authors named "Kelley Kearns"
Electrophoresis
September 2024
Article Synopsis
- Double-stranded RNA (dsRNA) is an unintended product of in vitro transcription that can trigger inflammation by activating immune receptors.
- This dsRNA presence, though only 0.1%-0.5% of total RNA, complicates its identification during analysis, making its exact sizes largely unknown.
- A new dsRNA-specific immuno-northern blot technique offers a clearer understanding of dsRNA size distributions, potentially aiding in studies related to dsRNA synthesis and removal for therapeutic RNA applications.
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