Publications by authors named "Kelda G Schonhoff"
Patients with acute myeloid leukemia (AML) who have failed hypomethylating agents (HMA) have a poor prognosis. We examined whether high intensity induction chemotherapy could abrogate negative outcomes in 270 patients with AML or other high-grade myeloid neoplasms. Prior HMA therapy was significantly associated with a lower overall survival (OS) as compared to a reference group of patients with secondary disease without prior HMA therapy (median 7.
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- * Results show that newly diagnosed patients on CLAG-M experienced a higher frequency of microbiologically confirmed infections (27.8%) compared to those on 7+3 (16.5%).
- * Among patients with relapsed/refractory disease, infection rates were even higher (50.7%), highlighting the significant role infections play in morbidity and mortality, necessitating better infection prevention strategies.