SLAMF7-expressing B cells as crucial mediators in the pathogenesis of rheumatoid arthritis-interstitial lung disease.

The regulatory factors involved in rheumatoid arthritis (RA) complicated with interstitial lung disease (ILD) (RA-ILD) remain unknown. Due to the cross-sectional nature of our study, our aim was to explore the role of the signalling lymphocytic activation molecule family (SLAMF) in RA-ILD by analysing synovial and lung samples from the Gene Expression Omnibus, animal models, and clinical samples.We collected peripheral blood mononuclear cells from patients for flow cytometry analysis of B cells, SLAMF1 protein, and SLAMF7 protein.

Macrocycle Self-Assembly Hydrogel for High-Efficient Oil-Water Separation.

Supramolecular hydrogels involved macrocycles have been explored widely in recent years, but it remains challenging to develop hydrogel based on solitary macrocycle with super gelation capability. Here, the construction of lantern[3 ]arene-based hydrogel with low critical gelation concentration (0.05 wt%), which can be used for efficient oil-water separation, is reported.