Publications by authors named "Kekai Wang"
Article Synopsis
- The study aims to understand the development of Irritable Bowel Syndrome with Diarrhea (IBS-D) using bioinformatics and differential microRNA analysis in rat colon tissue.
- It involves creating an IBS-D model in rats through specific stress techniques, followed by sequencing to identify key microRNAs, particularly miR-6324, and evaluating their target genes and functions through various analytical methods.
- The findings suggest that miR-6324 plays a potential role in IBS-D by influencing gene expression related to cell growth and cancer pathways, presenting it as a possible target for future research and treatment strategies.
Lenalidomide (LEN) has been reported to exert antitumor, anti-inflammatory, anti-angiogenic and immunomodulatory activities. However, the effects of LEN in spinal cord injury (SCI) are yet to be fully elucidated. The present study was conducted to identify whether LEN has a healing effect on SCI and to determine the underlying mechanism of action.
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