IEEE J Biomed Health Inform
July 2024
The real-world Electronic Health Records (EHRs) present irregularities due to changes in the patient's health status, resulting in various time intervals between observations and different physiological variables examined at each observation point. There have been recent applications of Transformer-based models in the field of irregular time series. However, the full attention mechanism in Transformer overly focuses on distant information, ignoring the short-term correlations of the condition.
View Article and Find Full Text PDFBackground: Linked-read sequencing technologies generate high-base quality short reads that contain extrapolative information on long-range DNA connectedness. These advantages of linked-read technologies are well known and have been demonstrated in many human genomic and metagenomic studies. However, existing linked-read analysis pipelines (e.
View Article and Find Full Text PDFAlthough long-read sequencing enables the generation of complete genomes for unculturable microbes, its high cost limits the widespread adoption of long-read sequencing in large-scale metagenomic studies. An alternative method is to assemble short-reads with long-range connectivity, which can be a cost-effective way to generate high-quality microbial genomes. Here, we develop Pangaea, a bioinformatic approach designed to enhance metagenome assembly using short-reads with long-range connectivity.
View Article and Find Full Text PDFZhongguo Zhen Jiu
February 2024
The paper introduces professor 's clinical experience in treatment of cyclomastopathy. In pathogenesis, cyclomastopathy is relevant with dysfunction of the thoroughfare vessel and the conception vessel, the stagnation of blood and phlegm and the stagnation of liver . The principle of treatment prefers to unblocking the circulation of and blood and adjusting the balance between and .
View Article and Find Full Text PDFHui Yang Jiu Ji (HYJJ) decoction has been applied as a prescription of traditional Chinese medicine for the treatment of chronic heart failure (CHF). However, its comprehensive molecular mechanism remains unclear now. Our study aimed to explore the possible function and lncRNA-miRNA regulation networks of HYJJ on CHF induced by doxorubicin (DOX) in rats.
View Article and Find Full Text PDFZhongguo Zhen Jiu
November 2021
Professor -'s experience of acupuncture technique for shoulder arthralgia is summarized. According to the location of pain, shoulder arthralgia is divided into hand- type, hand- type, hand-g type, hand- type and mixed type. The acupoint selection is based on acupuncture technique, and Shugu (BL 65) or Feiyang (BL 58) are selected for hand- type, Taichong (LR 3) for hand- type, Taixi (KI 3) and Dazhong (KI 4) for hand- type, and Taibai (SP 3) or Diji (SP 8) for hand- type.
View Article and Find Full Text PDFBinary data with one-class missing values are ubiquitous in real-world applications. They can be represented by irregular tensors with varying sizes in one dimension, where value one means presence of a feature while zero means unknown (i.e.
View Article and Find Full Text PDFJ Healthc Inform Res
December 2020
Clinical time series imputation is recognized as an essential task in clinical data analytics. Most models rely either on strong assumptions regarding the underlying data-generation process or on preservation of only local properties without effective consideration of global dependencies. To advance the state of the art in clinical time series imputation, we participated in the 2019 ICHI Data Analytics Challenge on Missing Data Imputation (DACMI).
View Article and Find Full Text PDFBackground: There is a critical need to examine whether mining of molybdenum (Mo) ore will affect Mo absorption and translocation by plants at a community level.
Methods: Indigenous plants and their rhizospheric soil (0-20 cm) growing in two different areas including the mining and the unexploited areas were collected from the Luanchuan Mo mine-one of the largest Mo mines in Asia. The concentrations of Mo and other heavy metals of plants or soil were measured by ICP-AES.
Zhongguo Zhen Jiu
March 2020
Professor - is good at identifying the location of the disease by using meridian examination. With rich knowledge of the classics, combined with his own clinical experience, professor puts forward "spasmodic muscle-tendon leads to pain", and the effect of (acupuncture at joints) is superior. Moreover, according to , he has summarized new method of , which uses fewer acupoints but achieves satisfactory efficacy.
View Article and Find Full Text PDFObjective: To observe the effect of acupuncture therapeutic courses on rheumatoid arthritis.
Method: Forty-seven patients were treated with acupuncture for 6 courses and at the end of the third and sixth course of treatment, the therapeutic effects of acupuncture on morning rigidity, swelling and pain of joints as well as rheumatoid factor (RF), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were observed.
Result: At the end of the third course, the markedly effective rate was 34.