Publications by authors named "Kejiao Ma"
Unlabelled: Avian leukosis virus subgroup J (ALV-J) poses a significant threat to the poultry industry; yet, our understanding of its replication and pathogenic mechanisms is limited. The Ten-Eleven Translocation 2 (TET2) is an indispensable regulatory factor in active DNA demethylation and immune response regulation. This study reports a significant and time-dependent decrease in TET2 levels following ALV-J infection and shows that the reduction of TET2 protein is mediated by the autophagy pathway.
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- This study investigates mobile genetic elements (MGEs) that carry antibiotic resistance genes (ARGs) from a common bacteria causing hospital infections, aiming to enhance the understanding of their genetic characteristics and evolution.
- Fifteen clinical isolates were sequenced to identify 15 novel MGEs, alongside others from a database, leading to the classification of 19 MGEs into three groups based on their structures and origins.
- Results indicate significant diversity among MGEs, with at least 36 ARGs found linked to resistance against multiple antibiotics, underscoring the ongoing evolution and complexity of these genetic elements in terms of antibiotic resistance.