A high-efficiency Tm:YLF laser at 2.3 µm is demonstrated based on a dual-wavelength pumping scheme with 790 nm LD and a tunable Yb:CALGO laser at around 1.05 µm.
View Article and Find Full Text PDFDouble plant homeodomain finger 2 (DPF2), belonging to the d4 family of structural domains, has been associated with various human malignancies. However, its impact on hepatocellular carcinoma (HCC) remains unclear. The objective of this study is to elucidate the role of DPF2 in the diagnosis and prognosis of HCC.
View Article and Find Full Text PDFObjective: Baicalin has antioxidative, antiviral, and anti-inflammatory properties. However, its ability to alleviate oxidative stress (OS) and DNA damage in liver cells exposed to aflatoxin B (AFB), a highly hepatotoxic compound, remains uncertain. In this study, the protective effects of baicalin on AFB-induced hepatocyte injury and the mechanisms underlying those effects were investigated.
View Article and Find Full Text PDFEfficient diode-pumped continuous-wave (CW) and wavelength tunable Tm:YAP lasers based on the vibronic and electronic transitions are investigated. A total maximum output power of 4.1 W is achieved with multi-wavelength output around 2162 nm and 2274 nm, corresponding to a slope efficiency of 29.
View Article and Find Full Text PDFThe biaxially-oriented PA56/512 has excellent mechanical strength, extensibility and water-oxygen barrier properties and has broad application prospects in green packaging, lithium battery diaphragm and medical equipment materials. The correlation between the aggregation structure evolution and macroscopic comprehensive properties of copolymer PA56/512 under biaxial stretching has been demonstrated in this work. The structure of the random copolymerization sequence was characterized by C Nuclear magnetic resonance (NMR).
View Article and Find Full Text PDFIn this paper, a high-power all-solid-state ultrafast 2 µm mode-locked laser is investigated. The particularity of this laser is the simultaneous utilization of two Tm:YAP crystals in the same resonant cavity, independently pumped by two laser diodes. Using a 20% output coupler, pulses with output power as high as 1.
View Article and Find Full Text PDFThis study was aimed to investigate the prognostic value and clinical significance of sarcosine dehydrogenase (SARDH) in hepatocellular carcinoma (HCC) and to explore the underlying mechanisms. The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), HPA and CPTAC databases were adopted to analyze the expression of SARDH mRNA and protein between normal liver tissue and HCC, and examine their relationship with clinicopathological features. Kaplan-Meier analysis, Cox regression, as well as nomogram were adopted to explore the prognostic value of SARDH in HCC.
View Article and Find Full Text PDFSepsis is a major disease that threatens human life and health. Clinically, it is mainly based on supportive treatment and lacks specific treatment methods. Acupuncture has important clinical significance in the prevention and treatment of sepsis.
View Article and Find Full Text PDFA high-efficiency, high-energy, narrow bandwidth, hundred-nanosecond pulse width 355 nm ultraviolet (UV) laser was realized. A high-energy single-frequency 1064 nm fundamental laser was demonstrated firstly with multistage end-pumped preamplifiers and side-pumped main amplifiers. The corresponding pulse energy, repetition rate, pulse duration, bandwidth, and beam quality factor M were determined to be 221 mJ, 100 Hz, 156 ns, 2.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is the most common type of primary liver cancer. HCC with liver fluke infection could harbor unique biological behaviors. This study was aimed at investigating radiomics features of HCC with liver fluke infection and establishing a model to predict the expression of cytokeratin 7 (CK7) and cytokeratin 19 (CK19) as well as prognosis at the same time.
View Article and Find Full Text PDFObjective: This study aimed to investigate the role of squamous cell carcinoma antigen recognized by T cells 3 (SART3) in hepatocellular carcinoma (HCC).
Methods: SART3 expression and prognostic value were analyzed in TCGA and GEO datasets. The diagnostic value and prognostic significance of SART3 were determined using immunohistochemistry in the Guangxi cohort.
We analyzed the prognostic value and potential molecular mechanisms of the members of integrin β (ITGB)superfamily in hepatocellular carcinoma (HCC) using data from The Cancer Genome Atlas (TCGA), cBioPortal, Gene Expression Profiling Interactive Analysis (GEPIA), Human Protein Atlas (HPA) HPA, Search Tool for the Retrieval of Interacting Genes/Proteins, GeneMANIA, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), TIMER and Gene set enrichment analysis (GSEA) databases. ITGB4/5 mRNA was upregulated in HCC tissues in contrast to the normal liver tissues, whereas ITGB2/3/8 levels were lower in the former. ITGB4 was the most frequently mutated ITGB gene in HCC.
View Article and Find Full Text PDFMulti-pulse dynamic patterns have been experimentally documented in a passively mode-locked (PML) erbium-doped fiber (EDF) laser using an SbS-PVA saturable absorber (SA). The fundamental mode-locking operation, with a repetition rate of ∼3.22 MHz, a pulse width of ∼2.
View Article and Find Full Text PDFElectrocatalytic water splitting is one of the most efficient ways of producing green hydrogen energy. The design of stable, active, and efficient electrocatalysts plays a crucial role in water splitting for achieving efficient energy conversion from electrical to hydrogen energy, aimed at solving the lingering energy crisis. In this work, CNT composites modified with CoP-VP composites (CoVO-10-CNT-450P) were formed by carbonising a pencil-like precursor (CoVO-HO) and growing carbon nanotubes in situ, followed by in situ phosphorylation on the carbon nanotubes.
View Article and Find Full Text PDFCascade transitions of Ho:I→I and I→I provide a platform for a dual-wavelength mid-infrared (MIR) laser. In this paper, a continuous wave cascade MIR Ho:YLF laser operating at 2.1 and 2.
View Article and Find Full Text PDFBackground: Great attention has been attached to the quality of nursing along with the development of medical treatment, which gives rise to the higher demand for colleges to cultivate high-quality nursing students, as well as the higher standard for teaching performance of the nursing faculty.
Objective: This study aimed to investigate the effect of teachers' job burnout on teaching ability among nursing teachers in Chinese colleges and to examine the mediating role of social support in this relationship based on the Person-context interaction theory.
Design: A cross-sectional descriptive design has been adopted.
Objective: To assess the diagnostic value and clinical significance of nucleoporin 107 (NUP107) in hepatocellular carcinoma (HCC), and explore the possible mechanisms.
Methods: The transcriptomic and clinical data of HCC patients were retrieved from The Cancer Genome Atlas (TCGA) and GEO databases. Tissue specimens were collected from HCC patients in the Guangxi area.
A diode-pumped self-Q-switched 2.74 µm Er:LuO crystal solid-state laser has been experimentally and theoretically studied. Without any additional modulation elements, stable self-Q-switched pulses with a pulse width of 145.
View Article and Find Full Text PDFWe firstly report a high pulse repetition rate (101.4 MHz) nonlinear post-compression based on the normal dispersion fiber (NDF) operating in 2-µm wavelength region. With only one-stage NDF-based nonlinear pulse compressor, the 2-µm ultrafast laser pulses are compressed from ∼460 fs down to 70 fs, corresponding to ∼10.
View Article and Find Full Text PDFThe choice of coping style of recruits under psychological stress in the process of military task execution has been an important topic in the promotion of military operations and cohesion of military forces. Taking a positive coping style under psychological stress can help recruits overcome the negative effects of stress and improve military morale and group combat effectiveness. Although soldiers' psychological stress in the process of military mission execution having an impact on coping style has been studied by a large body of literature, very little literature has focused on the mechanism of self-efficacy and social support between recruits' psychological stress and coping style from the person-environment fit perspective.
View Article and Find Full Text PDFA modified Frantz-Nodvik (F-N) equation and a simple one-dimensional unfolded slicing model for numerically simulating high-power Innoslab picosecond amplifier are developed for the first time. The anisotropic stimulated emission cross-section of laser crystal, the influence of the tilted optical path, the spatial overlap of the seed and pump laser, as well as the pump absorption saturation effect are considered. Based on the as-developed model, 4-, 6- and 8-pass schemes high-power Nd:YVO Innoslab picosecond amplifiers are designed with output powers of 76.
View Article and Find Full Text PDFIn this paper, a laser diode (LD) pumped passive mode-locking Tm,Ho:GAGG laser based on a semiconductor saturable absorber mirror (SESAM) is reported. By adjusting the group delay dispersions inside the laser cavity and transmissions of the output couplers (OCs), a shortest pulse duration of 10.84 ps at 2089.
View Article and Find Full Text PDFIn this paper, antimony trisulfide (SbS) was successfully prepared with the liquid phase exfoliation method and embedded into polyvinyl alcohol (PVA) as a saturable absorber (SA) in a passively mode-locked Er-doped fiber laser for the first time. Based on SbS-PVA SA with a modulation depth of 4.0% and a saturable intensity of 1.
View Article and Find Full Text PDFWe report the characteristics of a diode-end-pumped, high-repetition-rate, acoustic-optic (AO) Q-switched Tm:YLF laser operating from 5 kHz to 10 kHz. In the continuous-wave (CW) regime, a maximum average output power of 8.5 W was obtained with a slope efficiency of 30.
View Article and Find Full Text PDFIn the current study, layered metallic vanadium disulfide (VS) is fabricated by a liquid-phase exfoliation method, and its microstructures as well as optical characteristics are investigated. Based on first-principles calculations, the band structure and density of the states of both bulk T-VS and monolayer H-VS are illustrated, showing the metallic behavior with a zero band gap. By using VS as the saturable absorber in a doubly Q-switched Tm:YAP laser with an EOM, the Q-switching laser pulses at 2 μm with 22 ns and 200 Hz are generated, corresponding to the single pulse energy of 755 μJ and the peak power of 34.
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