Displacement and stress response of open-web girders under near field explosive loading.

This study employed numerical simulation to investigate the dynamic response characteristics of open-web girders subjected to proximity blast loading and to compare these characteristics with those of solid-web girders. The research utilized the Coupled Eulerian-Lagrangian (CEL) method for simulation, effectively combining the advantages of both Eulerian and Lagrangian approaches. This method mitigated issues related to mesh distortion while accurately modeling the damage inflicted by blast loads on the structures.

Graph Feature Refinement and Fusion in Transformer for Structural Damage Detection.

Structural damage detection is of significance for maintaining the structural health. Currently, data-driven deep learning approaches have emerged as a highly promising research field. However, little progress has been made in studying the relationship between the global and local information of structural response data.

Failure mechanism and bearing force of CFRP strengthened square hollow section under compressive load.

Carbon fibre-reinforced polymer (CFRP) plates can efficiently repair or enhance the mechanical properties of the square hollow section. However, the loading end of such a CFRP-strengthened member is prone to local bearing failure under compressive load. Given this limitation, an innovative CFRP-plate-strengthened square hollow section composite member (CFRP-SHSCM) was raised, and the thick-walled section was welded on both ends of the thin-walled steel column.

The effects of protein-rich extract from Rhizoma Gastrodiae against cerebral ischemia/reperfusion injury via regulating MAPK and PI3K/AKT signaling pathway.

Background: Rhizoma Gastrodiae is a highly valuable traditional Chinese medicine and functional health food that has been used in China to treat neurological disorders for thousands of years. Rhizoma Gastrodiae contains various of biological activities, such as antioxidative, neuroprotective, learning improvement, anxiolytic, and antidepressant effects. However, no studies have been conducted to explore the effects of the protein components in Rhizoma Gastrodiae (GEPS) and its potential protective effects against ischemic stroke.

A novel alcohol steamed preparation from Blume: Pharmacological assessment of a functional food.

Rhizoma Gastrodia (Orchidaceae; Blume), the rhizome of Blume (GE), is traditionally used as both a medicinal and functional food, with proven efficacy in treating mental disorders. In traditional processing, GE is washed, steamed with water, dried, and sliced. In this study, a novel processing technology-alcohol steamed GE (AGE) was proposed as an alternative.

Experimental Mechanical Properties and Numerical Simulation of C80 Concrete with Different Contents of Stone Powder.

In this paper, we show the influence of stone powder content on the mechanical properties of concrete by experiments and numerical simulations. In numerical simulation, this paper proposed a method whereby the stone powder in the numerical simulation of concrete is considered by the mechanical performances of mortar with the stone powder. The results of numerical models established based on inclusion theory and random aggregate distribution were basically consistent with the experiment, which indicated that the simulation method of concrete under different stone powder was feasible.

P- Hydroxybenzyl Alcohol Alleviates Oxidative Stress in a Nonalcoholic Fatty Liver Disease Larval Zebrafish Model and a BRL-3A Hepatocyte the Nrf2 Pathway.

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and it has gradually become the main disease burden in the world. However, the pathogenesis of NAFLD is complex, involving such things as dyslipidemia, oxidative stress, inflammation, etc. This brings to the table a significant challenge for drug development, and there is still no drug approved by the FDA on the market to treat the disease.

Ultrathin Quasibinary Heterojunctioned ReS/MoS Film with Controlled Adhesion from a Bimetallic Co-Feeding Atomic Layer Deposition.

Heterojunctioned transition-metal dichalcogenide (TMD) films with regulatable interface adhesion have shown broad application prospects in the design of advanced materials and the manufacturing of novel functional devices. To date, the controlled fabrication of TMD heterojunctions or heterojunction-rich films with tailorable thickness and composition has proved challenging. Herein, a bimetallic co-feeding atomic layer deposition (ALD) system was developed capable of fulfilling these requirements.

A Novel Biosensor Based on Molybdenum Disulfide (MoS ) Modified Porous Anodic Aluminum Oxide Nanochannels for Ultrasensitive microRNA-155 Detection.

Artificial photoresponsive nanochannels have attracted widespread attention because of their capacity to achieve ion transport through light modulation. Herein, a biosensor for ultrasensitive miRNA-155 detection is devised based on molybdenum disulfide (MoS ) modified porous anodic aluminum oxide (AAO) photoresponsive nanochannels by atomic layer deposition (ALD). According to the optimized experimental results, when the cycles of ALD, the wavelength, and the power of the excitation laser are 70 cycles, 450 nm, and 80 mW, respectively, the most supreme photocurrent performance of these photoresponsive nanochannels are obtained.

MoS-ReS Heterojunctions from a Bimetallic Co-chamber Feeding Atomic Layer Deposition for Ultrasensitive MiRNA-21 Detection.

Rhenium disulfide (ReS), which possessed a unique direct band gap from the bulk to monolayer, played a very important role in establishing optoelectronic devices, while the rapid recombination of electron-hole pairs might hinder its further applications. Therefore, to improve its photocurrent performance, a bimetallic co-chamber feeding atomic layer deposition (ALD) with a precise dose regulation strategy was used to fabricate MoS-ReS heterojunctions with a controllable Mo-to-Re ratio in this work. Furthermore, because of the controlled addition of Mo atoms, the electron-transfer capacity, carrier mobility, and photocurrent response of these heterojunctions were significantly improved among which the sample obtained under 100 supercycles (one supercycle for this sample consists of the following in turn: one ReCl pulse, one HS pulse, one ReCl pulse, one MoCl pulse, and one HS pulse; the real Mo-to-Re ratio = 57.

Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model.

Non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is the most common chronic liver disease in the world. However, there are still no drugs for NAFLD/NASH in the market. Gastrodin (GAS) is a bioactive compound that is extracted from which is used as an active compound on nervous system diseases.