A MicroRNA-1-Mediated Inhibition of the NF-κB Pathway by the JAK-STAT Pathway in the Invertebrate .

The JAK-STAT and NF-κB pathways are conserved cellular signaling cascades orchestrating a variety of biological processes. The regulatory interactions between these two pathways have been well studied in vertebrates but less concerned in invertebrates, hindering further understanding of immune signaling evolution. The Pacific white shrimp is now an important model for studying invertebrate immunity and cellular signaling mechanisms.