A case of nontraumatic urethral rupture possibly induced by prostatic abscess.

We herein report a rare case of nontraumatic urethral rupture. The patient presented with oliguria, perineal pain and anorexia, and a 3 cm fistula was located in the perineum. Computed tomography revealed a retroperitoneal abscess invading the urethra, and a retrograde urethrogram revealed the rupture of the membranous urethra.

Predictive ability of renal cortex enhancement in dynamic computed tomography for residual renal function after nephroureterectomy: Comparison with Tc-diethylenetriaminopentacetic acid renography and validation study.

Objective: To estimate postoperative residual renal function after radical nephroureterectomy for upper tract urothelial carcinoma using the preoperative dynamic computed tomography renal cortex enhancement ratio in comparison with the split kidney glomerular filtration rate measured by Tc-diethylenetriaminopentacetic acid renography.

Methods: A total of 47 patients who received radical nephroureterectomy and underwent both preoperative dynamic computed tomography and renography were the model-development cohort; and 109 patients who underwent dynamic computed tomography alone were the validation cohort. Postoperative renal function of the unremoved kidney was estimated using the following formulas: preoperative estimated glomerular filtration rate × the percentage of total renal cortex radiodensity for the intact kidney in Hounsfield units obtained from corticomedullary phase images in the computed tomography-based model, or the percentage of the total glomerular filtration rate measured by renography in the nuclear model.

Prognostic Value of Albumin/Globulin Ratio in Patients with Upper Tract Urothelial Carcinoma Patients Treated with Radical Nephroureterectomy.

Background/aim: We investigated the prognostic role of the albumin/globulin ratio (AGR) in patients with upper tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy (RNU).

Patients And Methods: AGR was calculated as follows: AGR=serum albumin/(serum total protein-serum albumin). Associations of preoperative AGR with disease-free (DFS) and overall (OS) survival were assessed in 105 patients with UTUC undergoing RNU.

Performance of Quick Sequential (Sepsis Related) and Sequential (Sepsis Related) Organ Failure Assessment to Predict Mortality in Patients with Acute Pyelonephritis Associated with Upper Urinary Tract Calculi.

Purpose: The Third International Consensus Definitions for Sepsis and Septic Shock Task Force proposed a new definition of sepsis based on the SOFA (Sequential [Sepsis-related] Organ Failure Assessment) score and introduced a novel scoring system, quickSOFA, to screen patients at high risk for sepsis. However, the clinical usefulness of these systems is unclear. Therefore, we investigated predictive performance for mortality in patients with acute pyelonephritis associated with upper urinary tract calculi.

Effect of Preoperative Bacteriuria and Pyuria on Intravesical Recurrence in Patients with Upper Tract Urothelial Carcinoma Undergoing Radical Nephroureterectomy.

Background/aim: We investigated the effect of bacteriuria and pyuria on intravesical recurrence (IVR) in patients with upper tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy (RNU).

Patients And Methods: Preoperative bacteriuria and pyuria were defined as urine containing ≥5 bacteria/high-power field (HPF) and >5 white blood cells/HPF, respectively. Their associations with IVR were evaluated in 97 patients with UTUC undergoing RNU.

External validation of TNM-C score in three community hospital cohorts for clear cell renal cell carcinoma.

Aim: To assess the general applicability of TNM-C scoring, which consists of TNM classification and preoperative C-reactive protein concentration, the predictive ability of the TNM-C score was externally validated for patients with clear cell renal cell carcinoma (ccRCC) at three community hospitals.

Patients And Methods: Seven hundred patients underwent radical or partial nephrectomy after being diagnosed with RCC. Out of the 700 patients, 518 with clear cell carcinoma served as the current study cohort.

Interactions between inducible nitric oxide synthase and cyclooxygenase-2 in response to ischaemia-reperfusion of rabbit bladder.

Objective: To investigate the interactions between inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in response to ischaemia-reperfusion (I/R) of rabbit bladder.

Materials And Methods: Rabbit bladders were exposed to 2 h of ischaemia by bilaterally clamping the major arteries entering the bladder and then a subsequent 36 h of reperfusion (I/R) with or without intraperitoneal administration of a selective iNOS inhibitor n-(3-(amynomethyl)benzyl)acetamidine (1400W) or a selective COX-2 inhibitor NS-398 given 1 h before killing. The bladder tissues were processed for isometric tension experiments, enzymatic NOS activitiy, tissue contents of nitrite/nitrate (NO(X) ), cyclic guanosine monophosphate (cGMP) and COX activity determined by prostaglandin E(2) (PGE(2) ) production.

Altered nitric oxide synthase, arginase and ornithine decarboxylase activities, and polyamine synthesis in response to ischemia of the rabbit detrusor.

Purpose: Little is known about L-arginine catabolism following ischemia in the bladder. We examined the changes in nitric oxide synthase, arginase and ornithine decarboxylase activity, polyamine biosynthesis and the ability to produce nitric oxide following ischemia of the rabbit bladder.

Materials And Methods: Bladder ischemia was created by ligation of a unilateral bladder artery.

[Myelolipoma of the adrenal gland presenting as upper abdominal symptoms: a case report].

A case of adrenal myelolipoma is presented. A 39-year-old woman was admitted to our hospital for further examination of a right adrenal mass, which was found by examination for nausea, vomiting and upper abdominal pain. Imaging analyses by computed tomography and magnetic resonance imaging revealed a round fatty mass.

[Initial assessment criteria for urination problems of the elderly--comparison of criteria for patients/caregivers/nurses, general practitioners, and urologists].

As the population ages rapidly, we need to establish a cost-effective system to assess and treat urination problems of the elderly. Recently, criteria have been developed for urologists to assess benign prostatic hyperplasia using the International Prostate Symptom Score (I-PSS), QoL index, urination function (maximal flow rates and residual urine volume) and prostate volume. It is suggested that patients with moderate to severe urination problems as measured by these criteria need to be treated but those with mild problems have no need for treatment.

[Criteria for general practitioners to assess treatment efficacy for urination problems of the elderly].

Criteria for general practitioners to assess treatment efficacy are needed to efficiently treat urination problems in the elderly. Recently, criteria have been developed for urologists to assess the efficacy of benign prostatic hyperplasia treatment using the International Prostate Symptom Score (I-PSS), QoL index and maximal flow rates. We examined whether these criteria can be applied to the general urination problems of the elderly men and women, with 85 male and 16 female subjects aged 50 and over.