Publications by authors named "Keith Mcintosh"
Initiation of vedolizumab did not provoke new-onset spondylarthritis in patients with inflammatory bowel disease: A prospective 24-week study with imaging assessments.
United European Gastroenterol J
September 2024
Article Synopsis
- - The study aimed to explore if starting vedolizumab (a medication for inflammatory bowel disease) was linked to new-onset spondyloarthritis (SpA) in patients with IBD through clinical evaluations and MRIs.
- - 24 patients with active ulcerative colitis or Crohn's disease participated, with assessments made before starting treatment and at 8 and 24 weeks.
- - Results showed that none of the patients developed new forms of axial or peripheral SpA after 24 weeks, indicating that vedolizumab does not appear to trigger these conditions in either TNF inhibitor-naïve or experienced patients.
Thin SiO interlayers are often formed naturally during the deposition of transition metal oxides on silicon surfaces due to interfacial reaction. The SiO layer, often only several atomic layers thick, becomes the interface between the Si and deposited metal oxide and can therefore influence the electrical properties and thermal stability of the deposited stack. This work explores the potential benefits of controlling the properties of the SiO interlayer by the introduction of pregrown high-quality SiO which also inhibits the formation of low-quality SiO from the metal-oxide deposition process.
View Article and Find Full Text PDFObjective: To gain mechanistic insights, we compared effects of low fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAP) and high FODMAP diets on symptoms, the metabolome and the microbiome of patients with IBS.
Design: We performed a controlled, single blind study of patients with IBS (Rome III criteria) randomised to a low (n=20) or high (n=20) FODMAP diet for 3 weeks. Symptoms were assessed using the IBS symptom severity scoring (IBS-SSS).
Computer-based virtual reality colonoscopy simulation improves patient-based colonoscopy performance.
Can J Gastroenterol Hepatol
April 2014
Background: Colonoscopy simulators that enable one to perform computer-based virtual colonoscopy now exist. However, data regarding the effectiveness of this virtual training are limited.
Objective: To determine whether virtual reality simulator training translates into improved patient-based colonoscopy performance.