Publications by authors named "Keith L Gray"
Article Synopsis
- Antiretroviral therapy (ART) is crucial for HIV patients, significantly lowering health risks and transmission rates; however, retaining patients on ART remains difficult in low and middle-income countries despite increased accessibility.
- In a nationwide study in Liberia tracking patients aged 15 and older from HIV care facilities, 41.8% were lost to follow-up and 6.6% died within 24 months, indicating substantial challenges in patient retention and adherence.
- Factors influencing retention included WHO clinical stages, with higher risk of loss-to-follow-up for patients in advanced stages, while older age groups showed a decreased risk of dropping out of care.
Objective: Interrupted time-series analyses, using 5 years of routinely collected health information system data, were conducted to estimate the magnitude of impact of the 2014-2015 Ebola virus disease (EVD) epidemic and determine trends in tuberculosis (TB) care services in Liberia.
Methods: A segmented linear regression model was used to generate estimates and predictions for trends for three TB service indicators before, during, and after EVD, from January 2013 to December 2017.
Results: It was found that the number of presumptive TB cases declined significantly at the start of the EVD outbreak, with an estimated loss of 3222 cases (95% confidence interval (CI) -5691 to -752; P = 0.