Publications by authors named "Keith J Schray"
Purpose: Side effects of diarrhea and steatorrhea diminish the therapeutic value of highly active antiretroviral therapy (HAART). We report in vitro studies of the effect of HAART drugs on the activity of pancrelipase, trypsin, and enterokinase and restoration of activity by subsequent addition of excess pancrelipase or colipase.
Methods: Commercial formulations of sixteen HAART drug formulations with solvent and four excipients were mixed with substrate.