Publications by authors named "Keilla M Paz E Silva"
Article Synopsis
- - The Oropouche virus (OROV), part of the Orthobunyavirus species, is an arthropod-borne zoonotic virus primarily transmitted by biting midges, causing significant outbreaks in humans, especially since the 1970s in the Amazon basin.
- - Since 2022, OROV outbreaks have spread more widely across Brazil and South America, with cases being reported as far away as Cuba, Italy, Spain, the USA, and Germany, establishing community transmission in all areas of Brazil.
- - Recent studies in Pernambuco state recovered and characterized two OROV isolates from the ongoing outbreak, revealing evidence of sustained transmission and highlighting the need for further research on the virus's transmission cycles to implement effective control
Article Synopsis
- - Dengue virus serotype 2, genotype Cosmopolitan (DENV-2-GII), is widely distributed and was newly identified in Brazil, having been present in other regions since 2019.
- - A study sequenced 237 confirmed DENV-2 cases from March 2021 to March 2023, discovering that DENV-2-GII circulates in all areas of Brazil, having been introduced multiple times between 2020 and 2022.
- - Despite its presence, DENV-1 dominated the Brazilian dengue epidemic in 2022, suggesting pre-existing immunity from prior DENV-2-GIII infections may limit symptomatic cases of DENV-2-GII, highlighting the need for ongoing
Background: Cervical cancer is one of the most common female cancers and is caused by human papillomavirus (HPV). Viral infection leads to cell cycle deregulation by inactivating p53 and retinoblastoma protein by viral oncoproteins E6 and E7, respectively. Then, nuclear proteins such as DNA topoisomerase type IIa (TOP2A) and Ki-67 show increased expression because of increased cell division.
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