Publications by authors named "Keil N"

Background: Hemodialysis relies on accurate body mass (BM) assessment to determine ultrafiltration volumes, but we have not identified published practice patterns disclosing how to handle clothing mass. Here we investigated the potential impact of clothing mass on predialysis BM determination, hypothesizing that a standardized template for clothing mass estimation enhances accuracy, compared with conventional practice.

Methods: Measurements included dressed and undressed BM predialysis.

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SQANTI-reads leverages SQANTI3, a tool for the analysis of the quality of transcript models, to develop a read-level quality control framework for replicated long-read RNA-seq experiments. The number and distribution of reads, as well as the number and distribution of unique junction chains (transcript splicing patterns), in SQANTI3 structural categories are informative of raw data quality. Multi-sample visualizations of QC metrics are presented by experimental design factors to identify outliers.

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Kaposi's sarcoma-associated herpesvirus is the etiologic agent of Kaposi's sarcoma and two B-cell malignancies. Recent advancements in sequencing technologies have led to high resolution transcriptomes for several human herpesviruses that densely encode genes on both strands. However, for KSHV progress remained limited due to the overall low percentage of KSHV transcripts, even during lytic replication.

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Mass-deployable implementations for quantum communication require compact, reliable, and low-cost hardware solutions for photon generation, control and analysis. We present a fiber-pigtailed hybrid photonic circuit comprising nonlinear waveguides for photon-pair generation and a polymer interposer reaching of pump suppression and photon separation based on a polarizing beam splitter with polarization extinction ratio. The optical stability of the hybrid assembly enhances the quality of the entanglement, and the efficient background suppression and photon routing further reduce accidental coincidences.

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Exposure to direct solar radiation, high ambient temperature, lack of wind movement, coupled with own metabolic heat production, makes grazing dairy cows vulnerable to heat stress. In pastures, it would be beneficial to monitor heat stress by observable changes in behaviour. We hypothesised that grazing dairy cows exhibit behavioural changes due to increasing heat load in temperate climate.

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A lab-on-a-chip multichannel sensing platform for biomedical analysis based on optical silicon nitride (SiNx) microring-resonators (MRR) was established. The resonators were surface functionalized and finally combined with a microfluidic chamber for validation using an avidin-biotin ligand-binding assay. The results with a limit of detection (LOD) of 2.

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Artificial selection by humans, either through domestication or subsequent selection for specific breeding objectives, drives changes in animal cognition and behaviour. However, most previous cognitive research comparing domestic and wild animals has focused on companion animals such as canids, limiting any general claims about the effects of artificial selection by humans. Using a cognitive test battery, we investigated the ability of wild goats (non-domestic, seven subjects), dwarf goats (domestic, not selected for milk production, 15 subjects) and dairy goats (domestic, selected for high milk yield, 18 subjects) to utilise physical and social cues in an object choice task.

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Monitoring the feeding and ruminating behaviour of ruminants can be used to assess their health and welfare. The MSR-jaw movement recording system (JAM-R) can automatically record the jaw movements of ruminants. The associated software Viewer2 was developed to classify these recordings in adult cattle and calculate the duration and number of mastications of feeding and ruminating.

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Even in temperate climate regions, an increase in ambient temperature and exposure to solar radiation can cause heat stress in lactating dairy cows. We hypothesised that grazing dairy cows exhibit short-term physiological changes due to increasing heat load under moderate climate conditions. Over two consecutive summers, 38 lactating Holstein dairy cows were studied in a full-time grazing system.

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For wireless networks beyond 5G, directivity and reconfigurability of antennas are highly relevant. Therefore, we propose a linear antenna array based on photodiodes operating at 300 GHz, and an optical phased array based on polymer waveguides to orchestrate the antennas. Due to its low thermal conductivity and high thermo-optical coefficient, the polymer chip enables highly efficient and crosstalk-free phase shifting.

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Mixed rations provide ruminants with a balanced diet by aiming to prevent selective feeding. However, this is a natural behavior of sheep and goats based on their dietary needs and the nutritional properties of feedstuffs. Therefore, the present study investigates non-lactating dairy sheep's and goats' acceptance of a mixed ration when it is offered as choice next to its single components.

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Feeding mixed rations is a widely used practice for cattle to ensure the intake of a balanced diet and to reduce competition for food. It is unknown, whether mixed rations have the same advantages for small ruminants because they differ from cattle in their feeding and social behaviour. In this observational pilot study, an array of feeding and social behaviour of dairy goats and sheep fed ad libitum with mixed rations on Swiss farms was investigated.

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When cross-sucking persists beyond calf-hood, it represents an important problem in dairy heifers and cows. It can cause teat injuries and severe mastitis and lead to significant economic losses. The «SuckStop Müller,» a novel anti-sucking device, is designed to give the calf a negative feedback when cross-sucking on a conspecific.

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Current evidence suggests that frequent exposure to situations in which captive animals can solve cognitive tasks may have positive effects on stress responsiveness and thus on welfare. However, confounding factors often hamper the interpretation of study results. In this study, we used human-presented object-choice tests (in form of visual discrimination and reversal learning tests and a cognitive test battery), to assess the effect of long-term cognitive stimulation (44 sessions over 4-5 months) on behavioural and cardiac responses of female domestic goats in subsequent stress tests.

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Given that domestication provided animals with more stable environmental conditions, artificial selection by humans has likely affected animals' ability to learn novel contingencies and their ability to adapt to changing environments. In addition, the selection for specific traits in domestic animals might have an additional impact on subjects' behavioural flexibility, but also their general learning performance, due to a re-allocation of resources towards parameters of productivity. To test whether animals bred for high productivity would experience a shift towards lower learning performance, we compared the performance of dwarf goats (not selected for production, 15 subjects) and dairy goats (selected for high milk yield, 18 subjects) in a visual discrimination learning and reversal learning task.

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Pre-participation screening and tracking of an athlete's functional status during a competitive season is essential to maintaining optimal performance. The sport of basketball had the third highest number of boys and girls participating during the 2018-2019 season (23), which typically occurs October to March each year. The Functional Movement Screen™ (FMS; 10) has been administered to some youth athletes from various sports, however, both males and females from basketball have not been studied extensively.

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This review describes the current state of knowledge relating to scientific literature on welfare indicators for goats. Our aim was to provide an overview of animal-based indicators for on-farm welfare assessments. We performed a literature search and extracted 96 relevant articles by title, abstract, and full-text screening.

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Cognitive research in long-lived species commonly involves using the same animals in different experiments. It is unclear whether the participation in cognitive tests can notably alter the performance of individuals in subsequent conceptually different tests. We therefore investigated whether exposure to cognitive tests affects future test performance of goats.

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The value society assigns to animal welfare in agricultural productions is increasing, resulting in ever-enhancing methods to assess the well-being of farm animals. The aim of this study was to review the scientific literature to obtain an overview of the current knowledge on welfare assessments for sheep and to extract animal-based welfare indicators as well as welfare protocols with animal-based indicators. By title and abstract screening, we identified five protocols and 53 potential indicators from 55 references.

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Background: The partograph is the most commonly used labour monitoring tool in the world. However, it has been used incorrectly or inconsistently in many settings. In 2018, a WHO expert group reviewed and revised the design of the partograph in light of emerging evidence, and they developed the first version of the Labour Care Guide (LCG).

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Contrafreeloading (CFL) is the phenomenon when animals work for a resource although an identical resource is available for free. Possible explanations for CFL are that animals seek context for species-specific behaviours or to control their environments. We investigated whether goats show CFL and whether breeding for productivity traits has altered its occurrence.

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The "outdoor veal calf" system was developed to encounter the demand for a veal fattening system that allows for reducing antimicrobial use without impairing animal welfare. Management improvements including direct purchase, short transportation, vaccination, three-week quarantine in individual hutches, and open-air housing in small groups in a roofed, straw-bedded paddock with a group hutch were implemented in a prospective intervention study (1905 calves, 19 intervention and 19 control farms, over one year): antimicrobial use was five times lower in "outdoor veal" farms compared to control farms ( < 0.001), but it was crucial to ensure that antimicrobial treatment reduction was not associated with decreased animal welfare, i.

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Article Synopsis
  • Magnetic skyrmions can move quickly in thin films using specific torques, showing potential for advanced computing despite limited studies on their thermal effects.
  • Thermally induced motion of skyrmions was explored in a custom low-pinning multilayer material, revealing that temperature greatly influences their dynamics.
  • This motion can enhance probabilistic computing devices, and studying it may provide insights into soft-matter phenomena like thermally induced roughness.
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We fabricated a simple sensor system for qualitative analysis of glycan-mediated interactions. Our main aim was to establish a ronbbust system that allowes drop-tests without complex fluidics. The test system should be usable in routine analytics in the future and bear sufficient sensitivity to detect binding events in the nanomolar range.

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