Publications by authors named "Keiko Ryo-Koriyama"
Background: Right ventricular (RV) failure in patients with pulmonary hypertension (PH) is associated with unfavorable clinical events and a poor prognosis. Elevation of right atrial (RA) pressure is established as a marker for RV failure. However, the additive prognostic value of RA mechanical function is unclear.
View Article and Find Full Text PDFObjectives: The closure of atrial septal defect (ASD) results in normalized left ventricular (LV) and right ventricular (RV) geometry, and can increase LV stroke volume (LVSV), but the parameters associated with this increase after the closure of ASD remain uncertain.
Methods: Seventy ASD patients, who underwent transcatheter closure, were studied. Their mean age was 57.
Article Synopsis
- * A study involving 40 patients with LVEF ≥ 35% revealed that those with mildly reduced LVEF (35-50%) experienced more significant deterioration in LV dyssynchrony during RV pacing than those with normal LVEF (≥ 50%).
- * The research suggests that patients with mildly reduced LVEF may benefit from cardiac resynchronization therapy (CRT) to mitigate the negative effects of RV pacing, particularly since baseline LVEF < 48% predicts significant LV dyssynchrony. *
Background: Although aortic valve intervention is recommended for virtually all symptomatic patients with aortic stenosis (AS), how urgently the intervention should be performed remains controversial. The aim of this study was thus to determine whether the preload reserve in response to leg-positive pressure (LPP) maneuver could serve for decision-making for AS patients awaiting aortic valve intervention.
Methods and results: Sixty-eight patients with symptomatic AS, who were referred for aortic valve intervention, were recruited.
Left ventricular (LV) diastolic dysfunction and longitudinal systolic dysfunction were identified in patients with diabetes mellitus (DM). This study's aim was to investigate the impact of LV longitudinal systolic function on LV diastolic function in DM patients with preserved LV ejection fraction (LVEF). We studied 177 DM patients with preserved LVEF (all ≥50%), and 82 age-, gender- and LVEF-matched healthy volunteers as control.
View Article and Find Full Text PDFMid-term right ventricular (RV) reverse remodeling after treatment in patients with pulmonary hypertension (PH) is associated with long-term outcome as well as baseline RV remodeling. However, baseline factors influencing mid-term RV reverse remodeling after treatment and its prognostic capability remain unclear. We studied 54 PH patients.
View Article and Find Full Text PDFLeft ventricular (LV) hypertrophy (LVH) is an independent cardiovascular risk factor for heart failure (HF) patients. The renin-angiotensin system plays a key role in LVH, and since olmesartan increases plasma angiotensin-(1-7) through an increase in angiotensin-converting enzyme-related carboxypeptidase (ACE2) expression, it was hypothesized to reduce LVH, unlike other angiotensin II receptor blockers (ARBs). The objective of this study was therefore to investigate the effects of a changeover from other ARBs to olmesartan on LVH in HF patients.
View Article and Find Full Text PDFBackground: Diabetic nephropathy is independently associated with longitudinal systolic dysfunction of the left ventricle (LV) in asymptomatic diabetes mellitus (DM) patients with preserved LV ejection fraction (LVEF). However, the effect of diabetic nephropathy on left atrial (LA) function remains unknown.
Methods and results: We studied 198 asymptomatic DM patients (LVEF ≥50%).
Background: Right ventricular (RV) systolic function is one of the most important determinants of outcome for pulmonary hypertension (PH) patients, but the factors influencing prognosis vary widely. Elevated right atrial (RA) pressure is reported to be one of these prognostic factors, but its functional importance has scarcely been assessed.
Methods: Eighty-two PH patients, all of whom underwent echocardiography and right heart catheterization, were recruited.