Publications by authors named "Keiko Ogaki"
Background: Complications associated with ultrasonographically guided percutaneous transhepatic liver biopsy (PTLB) after liver transplantation (LT) have been rarely reported, and there is no consensus about its safety. We retrospectively reviewed the safety and outcomes of PTLB after pediatric LT.
Methods: Between January 2008 and December 2019, 8/1122 (0.
Article Synopsis
- Early relaparotomy (surgical intervention within 3 months post-transplant) in pediatric liver transplant recipients is linked to worse survival outcomes compared to those who don't undergo this procedure.
- The study analyzed 265 pediatric liver transplant cases and found that 12.5% required early relaparotomy, which resulted in significantly lower recipient and graft survival rates.
- A higher preoperative Pediatric End-Stage Liver Disease (PELD) score was associated with the need for early relaparotomy, particularly in cases where the intervention was due to infections, which had the poorest prognosis.
Adverse Event: A drug interaction leading to greater exposure to tacrolimus.
Drug Implicated: Tacrolimus and Beni-Madonna (a new cultivar citrus categorized as 'Tangor').
The Patient: A 9-month-old girl with biliary atresia (body weight, 7.
Article Synopsis
- * Of the 279 pediatric LDLTs performed, complications arose in a notable percentage of patients, with IVR being the first treatment option for most complications, showing decent cure rates despite significant recurrence rates.
- * Overall graft survival rates were comparable between patients with and without complications, indicating that while IVR treatments are effective, ongoing follow-up is essential due to the risk of recurrence.