Publications by authors named "Keiko Nibu"

Article Synopsis
  • - The study examines the survival and development outcomes of 11 infants diagnosed with different types of brain tumors before the age of one, revealing generally poor prognoses with only six surviving patients.
  • - Surgical resection was performed on eight patients, with varying treatments including chemotherapy and radiotherapy, but five surviving patients showed signs of mental retardation.
  • - The findings highlight that, while some infants survived for extended periods, they require ongoing medical and social support due to potential developmental issues stemming from their conditions.
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Article Synopsis
  • The study introduces JN-DSRCT-1, the first permanent human cell line derived from a 7-year-old boy's pleural effusion suffering from desmoplastic small round cell tumor (DSRCT).
  • These cells maintain consistent morphological and histological features over 190 passages and 40 months, mirroring the original tumor's characteristics.
  • The cell line exhibits unique genetic markers, including a specific translocation and a chimeric gene fusion, making it valuable for researching DSRCT's pathology, biology, and potential treatments.
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"Guidelines on Blood Products Use" published in 1999 recommends restricting the use of fresh frozen plasma (FFP) solely to correct multiple coagulation factor deficiencies. We retrospectively studied the use of FFP in patients with massive intraoperative bleeding before and after publication of the new guidelines. There were 22 patients whose blood loss was more than their circulating blood volume (7% of body weight) in the past two years.

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