Publications by authors named "Keiko Naruto"
Article Synopsis
- Understanding tau polymerization is crucial for developing ways to inhibit the formation of harmful structures associated with neurodegenerative diseases.
- The tau protein has a microtubule-binding domain with key hexapeptide sequences that play a significant role in its polymerization process.
- This study reveals that a specific interaction between amino acids Ile308 and Tyr310 is vital for establishing a unique "steric zipper" structure in tau amyloid fibrils.
