Publications by authors named "Keiko Naito"
Article Synopsis
- The study analyzed the effectiveness of video laryngoscopes (VL) versus direct laryngoscopes (DL) during intubations performed by emergency department residents.
- Results showed that VL had a higher first-attempt success rate (77%) compared to DL (64%), which was statistically significant after adjusting for various factors.
- Additionally, using VL was linked to a lower occurrence of adverse events (both overall and minor), suggesting it may improve patient safety during intubation procedures.
Aim: Patients with head trauma who take antiplatelet or anticoagulant (APAC) agents have a higher rate of mortality. However, the association between these agents and mortality among blunt torso trauma patients without severe traumatic brain injury remains unclear.
Methods: Using the Japanese nationwide trauma registry, we conducted a retrospective cohort study including adult patients with blunt torso trauma without severe head trauma between January 2019 and December 2020.
Background: The use of benzodiazepines (BZDs) causes delirium, especially in elderly people. For this reason, suvorexant has been recommended as the first-line hypnotic in elderly patients. The aim of this study was to determine whether the first-line use of suvorexant, instead of BZDs, decreases referrals for delirium in elderly patients.
View Article and Find Full Text PDFBackground/aim: Chemoimmunotherapy is a promising treatment for various malignant diseases. In this study, we examined whether first-line chemoimmunotherapy using adoptive immune-cell therapy was effective for metastatic colorectal cancer (mCRC).
Patients And Methods: The therapeutic efficacy and safety of the standard first-line chemoimmunotherapy with adoptive αβ T cell therapy and bevacizumab were assessed using thirty-two patients with mCRC in our hospital.
Background: Adoptive immunotherapy for cancer has evolved through development of novel technologies for generating a large number of activated killer cells, such as αβ T-cells, γδ T-cells, and natural killer cells. There has been no prospective trial of combination therapy involving adoptive immunotherapy and first-line chemotherapy for stage IV colorectal cancer. The present pilot study aimed to evaluate the safety and feasibility of combination therapy involving adoptive immunotherapy and chemotherapy for stage IV colorectal cancer (COMVI study).
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the safety and effectiveness of performing hepatectomy (liver surgery) on patients with stage IV colorectal liver metastases after undergoing a specific form of chemoimmunotherapy using activated αβ T-cells.
- Five patients participated, who had received XELOX (capecitabine and oxaliplatin) combined with bevacizumab and T-lymphocytes before surgery, and their median age was 61.4 years.
- The results showed that various surgical approaches were taken without significant complications, indicating that this treatment pathway can be safely administered to patients.
Background/aim: Adoptive immunotherapy of cancer is evolving with the development of novel technologies that generate proliferation of large numbers of αβ and γδ T cells. We evaluated the safety and efficacy of the combination of adoptive immunotherapy using αβ T cells with chemotherapy for stage IV colorectal cancer (CRC).
Patients And Methods: Fifteen patients with advanced or recurrent CRC received XELOX + bevacizumab + ex vivo expanded αβ T lymphocytes as a first-line chemoimmunotherapy.
Objectives: The study investigated the provision of support by municipalities to assist people with mental disability securing a dwelling in the community.
Methods: In September 2008, a questionnaire was sent to welfare divisions concerned with people having mental disabilities in 1,805 municipalities nationwide. Responses were returned from 1,141 municipalities (recovery rate: 63.
Evaluation of electronic health records from viewpoint of patients.
Stud Health Technol Inform
December 2006
Objective: To clarify the impacts of electronic health records (EHRs) on patients, especially patient's satisfaction by using questionnaire.
Design: Surveys were conducted at three hospitals. One of them was surveyed three times; three-months before (pre-EHR) and three-months after (post-3mo EHR) and nine-months after implementation of EHR (post-9mo EHR).