Publications by authors named "Keiko Fukushi"
Bone-modifying agents (BMAs) have been widely used to reduce skeletal-related events, including pathological fractures. Herein, we aimed to clarify the incidence of pathological fractures caused by high-risk femoral bone metastases after palliative radiotherapy (RT) in the BMA era and evaluate the necessity of prophylactic surgical stabilization. We assessed 90 patients with high-risk femoral bone metastases, indicated by Mirels' scores ≥ 8, without pathological fractures and surgical fixations, who received palliative RT at our institution between January 2009 and December 2018.
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- - This study investigated the acute toxicity of hypo-fractionated radiotherapy in Japanese breast cancer patients post-surgery, focusing on two treatment cohorts: moderately hypo-fractionated (Cohort M) and ultra-hypo-fractionated (Cohort U).
- - A total of 123 patients were evaluated over 90 days after treatment, with the most common acute adverse events being grade 1 and 2, and no grade 3 or higher events reported.
- - The study concluded that the rates of acute toxicity from these radiotherapy methods were considered acceptable, with 15% for Cohort M and 10% for Cohort U experiencing grade 2 or higher adverse events.
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- The study examined the effects of postoperative radiotherapy (PORT) after salvage neck dissection for patients with cervical lymph node recurrence in oral cavity cancer, focusing on outcomes like survival and recurrence rates.
- After following 51 patients for about 7.4 years, the results showed a 7-year overall survival rate of 66.3% and a recurrence-free survival rate of 54.6%, with better outcomes for younger patients and those with isolated lymph node recurrence.
- While PORT was effective, some patients experienced side effects like severe acute mucositis (35%) and less common long-term issues like osteoradionecrosis (4%) and laryngeal stenosis (2%).
We report a case of a 63-year-old man with hemosuccus pancreaticus due to large pseudoaneurysm originating from the main trunk of the superior mesenteric artery (SMA). The patient was treated successfully with the double balloon-assisted coil embolization technique combined with proximal and distal balloon inflation in the short segment of the SMA. This technique preserved the pancreaticoduodenal arterial arcade and the supply to the distal part of the SMA by embolizing SMA in a short segment.
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- The study examined how low air humidity and low root temperature (LRT) affect water uptake, growth, and aquaporin gene expression in rice plants.
- Rice plants transpired 1.5- to 2-fold more in low humidity conditions, but LRT at 13°C further decreased transpiration and growth, especially under low humidity.
- The research found that low humidity increased the expression of certain aquaporin genes, indicating that aquaporins may help rice plants adapt to these stress conditions.
Root hydraulic conductivity (Lp(r)) and aquaporin amounts change diurnally. Previously, these changes were considered to be spontaneously driven by a circadian rhythm. Here, we evaluated the new hypothesis that diurnal changes could be triggered and enhanced by transpirational demand from shoots.
View Article and Find Full Text PDFThe role of root temperature T(R) in regulating the water-uptake capability of rice roots and the possible relationship with aquaporins were investigated. The root hydraulic conductivity Lp(r) decreased with decreasing T(R) in a measured temperature range between 10 degrees C and 35 degrees C. A single break point (T(RC) = 15 degrees C) was detected in the Arrhenius plot for steady-state Lp(r).
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