Capecitabine, an oral prodrug of 5 -fluorouracil, is a promising treatment for colorectal, breast, and gastric cancers, but often causes hand-foot syndrome(HFS), which is the most common dose-limiting toxicity. The aim of this study was to evaluate of the efficacy of the pharmacist in providing support at ambulatory therapy centers, especially for HFS. The HFS is a higher-incidence adverse event that may develop during chemotherapy with capecitabine.
View Article and Find Full Text PDFGan To Kagaku Ryoho
December 2007
The number of cancer patients and families desiring home-based care and out-patient chemotherapy has been increasing. Hence, a support system for home-based care is urgently needed for a patient with recurrent and/or advanced unresectable cancer who recieved cancer chemotherapy. The cancer therapy especially in patients with colorectal cancer could have expected an improvement of the prognosis utilizing FOLFOX/FOLFIRI, a standard therapy established in Europe and America.
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