Effect of enamel matrix derivative on bone formation around intraosseous titanium implant: An experimental study in canine model.

Background: The purpose of this study was to perform a histological, histomorphometrical, and immunohistochemical evaluation of the effect of Enamel matrix derivative (EMD) on bone formation around titanium dental implant.

Materials And Methods: In this animal study, 12 implants (10 × 3.8 mm) were inserted in the tibia bone of three dogs of Iranian breed.