Publications by authors named "Keiji Noguchi"

Liver stiffness (LS) has been reported to be a marker of liver congestion caused by elevated central venous pressure in heart failure (HF) patients. Recent studies demonstrated that LS could be non-invasively measured by virtual touch quantification (VTQ). However, its prognostic implication in patients with acute decompensated heart failure (ADHF) is unclear.

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Rationale: Adaptive servo-ventilation (ASV), a novel respiratory support therapy for sleep disorders, may improve cardiac function in heart failure (HF). However, the reasons that ASV improves cardiac function have not been fully studied especially in sympathetic nervous function (SNF). The purpose of the present study was to investigate the effects of ASV therapy on cardiac SNF in patients with HF.

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  • Cardiac sarcoidosis (CS) is a rare but serious condition that requires early diagnosis, and researchers are investigating the role of Propionibacterium acnes in its development.
  • *The study analyzed myocardial tissues from CS patients and compared them with those from patients with myocarditis and other heart diseases to identify the presence of P. acnes.
  • *Results showed that P. acnes was commonly found in granulomas and inflammatory foci in CS samples, suggesting a potential link between this bacterium and the disease, which could help differentiate CS from other cardiac conditions.
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  • Optimal medical therapy (OMT) and managing risk factors are vital for preventing serious heart and brain issues in patients after an acute coronary syndrome (ACS) event, especially in Japan.
  • The PACIFIC study involved 3,597 ACS patients, revealing that 229 experienced death or major events within a year of discharge; adherence to OMT was linked to fewer complications and better risk factor control.
  • The findings highlighted that controlling blood sugar levels post-discharge significantly reduces the risk of major adverse events (MACCE) in these patients, emphasizing the importance of proper management after hospitalization.
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  • Heart failure (HF) can lead to increased liver stiffness, which may indicate organ congestion, and the study used virtual touch quantification (VTQ) to measure this stiffness alongside kidney stiffness.
  • In a sample of 38 HF patients and 10 normal subjects, liver stiffness was found to be significantly higher in HF patients, while kidney stiffness did not show significant differences between the groups.
  • The study found that factors like central venous pressure and B-type natriuretic peptide levels were predictive of liver stiffness; treatment for HF led to a significant decrease in liver stiffness, indicating that VTQ could be a useful tool for monitoring liver congestion and treatment responses in HF patients.
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Adaptive servo-ventilation (ASV) has been attracting attention as a novel respiratory support therapy for heart failure (HF). However, the acute hemodynamic effects have not been compared between ASV and continuous positive airway pressure (CPAP) in HF patients.We studied 12 consecutive patients with stable chronic HF.

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Anomalous right coronary artery arising from the left sinus of Valsalva is a rare congenital abnormality. Percutaneous coronary intervention of the anomalous-origin right coronary artery can be challenging. Iatrogenic aorto-coronary dissection is a rare and life-threatening complication.

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It is possible to diagnose varicose vein from medical history and physical examinations including inspection and palpation. Non-contrast enhanced MRV (magnetic resonance venography) is becoming popular because it can be easily performed without being affected by the radiographer's skill. We thought that the use of MEDIC (multi echo data imaging combination) would enable us to delineate varicose veins within a short acquisition time and without need for synchronization or contrast enhancement.

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