Publications by authors named "Keiichiro Sano"

In this paper, a knittle pressure sensor was designed and fabricated by coating graphene/Polyvinylidene Fluoride nanocomposite on the knitted polyester substrate. The coating was carried out by a dip-coating method in a nanocomposite solution. The microstructure, surface properties and electrical properties of coated layers were investigated.

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In this study, the process for tuning the electrical properties of graphene/polyvinylidene fluoride (Gr/PVDF) nanocomposite films by a thermal annealing process is explored. The surface morphology and microstructure of the nanocomposite were characterized. The effect of temperature on the electrical conductivity was investigated by heating and cooling the sample from the room temperature up to 150 °C.

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Article Synopsis
  • Researchers are developing flexible and stretchable sensors to replace traditional rigid ones, focusing on a piezoresistive airflow sensor for measuring air speed in pipes.
  • The sensor uses a graphene/polyvinylidene fluoride nanocomposite film on a flexible substrate and shows improved resistance change with higher graphene concentrations, alongside tests for temperature effects and stretchability.
  • Experimental results matched simulations from COMSOL Multiphysics, showing a sensitivity of 1.21% kPa, making the lightweight, flexible sensor suitable for applications in ventilators, HVAC systems, and automotive industries.
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Chick embryos have been used as alternative experimental animals in various research fields, including virology, immunology, toxicology, oncology, and embryology. Until now, there have been no in vivo models using chick embryo to evaluate radiosensitizing activity. Here, the in vivo radiosensitizing activity of etanidazole, a well-known hypoxic cell radiosensitizer, was evaluated using tumor-bearing chick embryo.

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We presented here design, syntheses and inhibitory activities of novel hypoxia-targeting IDO hybrid inhibitors conjugated with an unsubstituted L-Trp as an IDO affinity moiety without inhibitor 1MT, such as L-Trp-TPZ hybrids 1 (TX-2274), 2 (UTX-3), 3 (UTX-4), and 4 (UTX-2). TPZ-monoxide hybrids 1 and 3 were good competitive IDO inhibitors, while TPZ hybrids 2 and 4 were uncompetitive IDO inhibitors. Among them TPZ-monoxide hybrid 1 have the strongest IDO inhibitory activity.

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