The Performance of GPT-3.5, GPT-4, and Bard on the Japanese National Dentist Examination: A Comparison Study.

Purpose This study aims to evaluate the performance of three large language models (LLMs), the Generative Pre-trained Transformer (GPT)-3.5, GPT-4, and Google Bard, on the 2023 Japanese National Dentist Examination (JNDE) and assess their potential clinical applications in Japan. Methods A total of 185 questions from the 2023 JNDE were used.

Squamous Cell Carcinoma of the Gingiva.

A 77-year-old woman presented with a 2-year history of denture sores at the left mandibular gingiva. She had no smoking history or alcohol use. Intraoral examination showed a cauliflower-like, 28 × 20 mm mass on the left mandibular gingiva without induration.

Intraoral hemorrhage caused by dental calculus: two case reports.

Intraoral hemorrhage is an undesirable and emergency condition, and it can also occur spontaneously. Clinicians sometimes face difficulty in identifying the hemorrhage points and the causes of hemorrhage, as well as difficulty in the hemostatic procedures. Here, the authors present two rare cases of spontaneous intraoral hemorrhage related to dental calculus.

Oral liposarcoma in elderly: Case report and literature analysis.

Rationale: Oral liposarcoma is an extremely rare lesion that is often clinically misdiagnosed as a benign lesion because of its asymptomatic and indolent clinical course. we report a case of atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) of buccal mucosa, provisionally diagnosed as lipoma.

Patient Concerns: A 97-year-old female was referred to dentistry and oral surgery department with an asymptomatic mass on the right buccal mucosa which had been present for an unknown period of time.

Celecoxib suppresses lipopolysaccharide-stimulated oral squamous cell carcinoma proliferation and .

Periodontitis is one of the most common chronic oral inflammatory conditions worldwide and is associated with a risk of developing oral squamous cell carcinoma (OSCC). is a major pathogen in periodontitis, and its lipopolysaccharide (LPS) promotes the expression of cyclooxygenase-2 (COX-2) in OSCC both and . Celecoxib is a selective COX-2 inhibitor; however, its antitumor effects on LPS-stimulated OSCC and the underlying molecular mechanism remain unclear.

The therapeutic potential of epigallocatechin‑3‑gallate against human oral squamous cell carcinoma through inhibition of cell proliferation and induction of apoptosis: In vitro and in vivo murine xenograft study.

Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors in the oral region. Despite current therapeutic strategies, the survival rate has not been improved for several decades. Thus, it is important to develop a novel approach for the treatment of OSCC.

Efficacy of aprepitant in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy.

Aims And Background: To evaluate the efficacy of a combination of aprepitant and conventional antiemetic therapy in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy (MEC).

Methods: Patients with advanced or recurrent lung cancer who were treated with MEC regimens at the Department of Respiratory Medicine, Fukuoka University Hospital, were included and classified into the following groups: control group (treatment: 5-HT3 receptor antagonists + dexamethasone) and aprepitant group (treatment: 5-HT3 receptor antagonists + dexamethasone + aprepitant). The presence or absence of chemotherapy-induced nausea and vomiting (CINV) was evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.