Publications by authors named "Keiichi Masuta"
Background: Measurement of brain natriuretic peptide (BNP) in plasma is useful for the diagnosis and prognosis of heart failure. However, the molecular forms of BNP, especially proBNP in the blood, have been poorly characterized.
Methods: To investigate the forms of proBNP in blood, antibodies against four proBNP synthetic peptides (1-13, 22-27, 28-40, and 47-54) were developed and characterized for their reactivity to proBNP by ELISA.
Background: Brain natriuretic peptide (BNP) is a vasoreactive peptide hormone, which is synthesized and secreted mainly from the heart ventricles.
Methods: Molecular forms of immunoreactive human brain natriuretic peptide (BNP) were examined. Chemically synthesized human BNP was added to whole blood samples from a healthy volunteer.