Publications by authors named "Kehuan Lin"
Background/objectives: Sleep quality is a critical factor for daytime functioning and chronic disease risk. We investigated the association between intakes of total protein and protein subtypes and sleep quality in three U.S.
View Article and Find Full Text PDFObjective: Gout flares are followed by transient major cardiovascular (CV) risk, implicating the role of inflammation; the aim of this study was to determine whether premature mortality rates in patients with gout and CV risk are independent of serum urate (SU) and atherosclerotic CV disease (ASCVD) risk factors.
Methods: Using serial US nationwide prospective cohorts, we evaluated the independent association of prevalent gout with all-cause and CV mortality, adjusting for SU, ASCVD risk factors, comorbidities, medications, and kidney function and compared mortality rates between the early (1988-1994 baseline) and late cohorts (2007-2016 baseline). We replicated late cohort findings among patients with gout in a nationwide UK cohort (2006-2010 baseline).
Article Synopsis
- The study investigates the prevalence of gout and serum urate levels across different racial and ethnic groups in the U.S., with a particular focus on previously unexamined disparities among Asian individuals.
- Data from the National Health and Nutrition Examination Survey (NHANES) and the UK Biobank were used to analyze trends from 2011 to 2018, revealing a significant increase in gout prevalence among Asian Americans.
- The findings indicate that, by 2017-2018, Asian Americans had a higher prevalence of gout (6.6%) compared to other racial groups, highlighting an urgent need to understand the socioclinical factors contributing to this disparity.
Introduction: This meta-analysis aimed to examine the association of child abuse with adult coronary heart disease risk and separately by abuse subtypes, including emotional abuse, sexual abuse, and physical abuse.
Methods: Data were extracted from studies published up through December 2021 and on the basis of research from PubMed, Embase, CINAHL, and PsycINFO. Studies were selected if they included adults with or without any type of child abuse and measured the risk of any type of coronary heart disease.
Objective: To examine whether the cross-sectional gene-diet interaction for prevalent hyperuricemia among women translates prospectively to risk of incident female gout.
Methods: We analyzed the interaction between genetic predisposition and adherence to a healthy dietary pattern (i.e.