Comparison of inhalational methoxyflurane (Penthrox®) and intramuscular tramadol for prehospital analgesia.

Introduction: Treatment of pain is an important component of prehospital care. Inhalational analgesia agents have attractive strengths, but there is a paucity of studies comparing these with more conventional agents. We aimed to compare inhalational methoxyflurane and intramuscular (IM) tramadol as first-contact analgesia in the Singapore national ambulance service.