Background: Emtricitabine (FTC) is a commonly prescribed anti-human immunodeficiency virus (HIV) drug that has been classified as an emerging environmental pharmaceutical micropollutant due to its poor metabolism, refractory nature to wastewater treatment, continuous discharge with wastewater effluent and accumulation in the aquatic environment. Although there are no reported limits and toxicity of the drug in the environment yet, it is crucial to develop onsite, rapid, selective and ultrasensitive water sensing systems for FTC to ensure efficient risk management and environmental sustainability.
Results: Herein, a molecularly imprinted poly(para-aminobenzoic acid) (MIP) was electrochemically prepared on iron oxide nanoparticles modified glassy carbon electrode (MIP/FeO NPs/GCE) for selective detection of FTC using differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS).
Tuberculosis (TB) is a worldwide burden whose total control and eradication remains a challenge due to factors including false positive/negative diagnoses associated with the poor sensitivity of the current diagnostics in immune-compromised and post-vaccinated individuals. As these factors complicate both diagnosis and treatment, the early diagnosis of TB is of pivotal importance towards reaching the universal vision of a TB-free world. Here, an aptasensor for signaling an interferon gamma (IFN-γ) TB biomarker at low levels is reported.
View Article and Find Full Text PDFThis study is a first-time report of the development of a mercaptosuccinic acid-nickel selenide quantum dots (MSA-NiSe QDs)-based electrochemical aptasensor for brain natriuretic peptide (BNP) detection. Herein, novel MSA-NiSe QDs were synthesized by microwave irradiation. Microscopic and structural analysis revealed that the QDs are spherical with an average diameter of 2 nm.
View Article and Find Full Text PDFWe report the preparation of poly (propylene imine) dendrimer (PPI) and CdTe/CdSe/ZnSe quantum dots (QDs) as a suitable platform for the development of an enzyme-based electrochemical cholesterol biosensor with enhanced analytical performance. The mercaptopropionic acid (MPA)-capped CdTe/CdSe/ZnSe QDs was synthesized in an aqueous phase and characterized using photoluminescence (PL) spectroscopy, ultraviolet-visible (UV-Vis) spectroscopy, transmission electron microscopy (TEM), X-ray power diffraction (XRD), energy dispersive X-ray (EDX) spectroscopy. The absorption and emission maxima of the QDs red shifted as the reaction time and shell growth increased, indicating the formation of CdTe/CdSe/ZnSe QDs.
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