Porcine bile acids improve performance by altering hepatic lipid metabolism and amino acid metabolism with different protein level diets in late laying hens.

As the extension of the egg-laying cycle, heightened energy and lipid metabolism cause excessive lipid accumulation, resulting in rapid decline in laying performance during the late laying period. Bile acids (BAs), synthesized from cholesterol in the liver, are potent metabolic and immune signaling molecules involved in lipid metabolism and the regulation of energy homeostasis. However, under different dietary protein levels, the role of BAs on hepatic lipid metabolism of laying hens at the late phase remains unclear.

Investigating the Effects of Dietary Bile Acids on Production Performance and Lipid Metabolism in Late-Phase Laying Hens.

Multiply adverse effects including declines in production performance and excessive fat deposition were noticed with the extension of the laying cycle in hens, which are pertinent to animal welfare and human food safety. This study aimed to investigate the effect of dietary supplementation of bile acids (BAs) on production performance and lipid metabolism in late-phase laying hens. A total of 144 70-week-old hens were distributed into three treatments with eight replicates per treatment, including the basal diet with 0 (Ctrl), 95.

Predictors of urinary heavy metal concentrations among pregnant women in Jinan, China.

Background: Toxic heavy metal exposure and insufficiency or excess of essential heavy metals may have negative effects on pregnant women's health and fetal growth. To date, the predictors of pregnant women's heavy metal exposure levels remain unclear and vary with different regions. The study intended to explore potential predictors of exposure to heavy metals individually and high co-exposure to heavy metal mixtures.

CMNet: deep learning model for colon polyp segmentation based on dual-branch structure.

Purpose: Colon cancer is one of the top three diseases in gastrointestinal cancers, and colon polyps are an important trigger of colon cancer. Early diagnosis and removal of colon polyps can avoid the incidence of colon cancer. Currently, colon polyp removal surgery is mainly based on artificial-intelligence (AI) colonoscopy, supplemented by deep-learning technology to help doctors remove colon polyps.

Dual ensemble system for polyp segmentation with submodels adaptive selection ensemble.

Colonoscopy is one of the main methods to detect colon polyps, and its detection is widely used to prevent and diagnose colon cancer. With the rapid development of computer vision, deep learning-based semantic segmentation methods for colon polyps have been widely researched. However, the accuracy and stability of some methods in colon polyp segmentation tasks show potential for further improvement.

Tri-branch feature pyramid network based on federated particle swarm optimization for polyp segmentation.

Deep learning technology has shown considerable potential in various domains. However, due to privacy issues associated with medical data, legal and ethical constraints often result in smaller datasets. The limitations of smaller datasets hinder the applicability of deep learning technology in the field of medical image processing.

MicroRNA-21 and its impact on signaling pathways in cervical cancer.

Oncogenic microRNA-21 (miR-21/miRNA-21) is a stable inhibitor of gene expression that is often upregulated in cervical cancer, a disease that affects the health of women and tends to transform and spread. Previous studies investigating miR-21 in biopsies and cells from cervical cancer patients have identified that miR-21 binds target mRNAs in signaling pathways or long non-coding RNAs (lncRNA). Furthermore, studies have elucidated the molecular mechanisms of two tumor necrosis factor α (TNF-α) signaling pathways that promote cell proliferation and inhibit cell apoptosis.

Amygdalin attenuates acute liver injury induced by D-galactosamine and lipopolysaccharide by regulating the NLRP3, NF-κB and Nrf2/NQO1 signalling pathways.

Acute liver injury (ALI) is a life-threatening syndrome accompanied by overwhelming inflammation. Amygdalin (AGD) has been reported to possess various biological activities, particularly anti-inflammatory activity. The current study was designed to assess the protective effects and underlying mechanisms of AGD against ALI induced by d-galactosamine (GalN) and lipopolysaccharide (LPS) in mice.

Association of miR-182 expression in amniotic fluid with intrauterine infection and brain injury in premature infants.

Changes of micro-ribonucleic acid-182 (miR-182) level in cases of intrauterine infection were investigated to explore the association between miR-182 level change and brain injury in premature infants. A total of 257 preterm infants born in obstetrics department of Jinan Maternity and Child Care Hospital from February 2015 to February 2017 were enrolled in this study. These preterm infants were divided into infected group (n=113) and uninfected group (n=144) based on pathological diagnosis results.

Atractylodin attenuates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome and TLR4 pathways.

Acute lung injury (ALI) arises from uncontrolled pulmonary inflammation with high mortality rates. Atractylodin (Atr) is a polyethylene alkynes and has been reported to possess anti-inflammation effect. Thus, we aimed to investigate the protective effect of Atr on lipopolysaccharide (LPS)-induced inflammatory responses ALI.

Combination therapeutic effects of high intensity focused ultrasound and Metformin for the treatment of adenomyosis.

Adenomyosis is a pathological gynaecological condition characterized by benign invasion of the endometrium into the myometrium. High intensity focused ultrasound (HIFU) is one of the most common therapeutic strategies for the treatment of adenomyosis. However, the efficacy of single HIFU therapy is insufficient for the treatment of patients with adenomyosis.

Projection-based disparity control for toed-in multiview images.

The multiview images captured by toed-in camera array can reproduce the 3D scene vividly with appropriate positive, negative, and zero disparities. However, it is a challenging task to adjust the depth of the scene according to requirements of visual effects. In this paper, we propose a novel disparity control method based on projection to solve this problem.

[Comparisons between NIR and HPLC fingerprint on quality stability of Shudihuang decoction pieces].

Objective: To establish a new method for evaluating quality stability of Shudihuang decoction pieces with near-infrared spectrum.

Method: Clustering analysis was used to distinguish different Shudihuang samples. And comparisons between NIR and HPLC fringerprint.

Research on processing medicinal herbs with multi-steps infrared macro-fingerprint method.

How to apply rapid and effective method to research medicinal herbs, the representative of complicated mixture system, is the current study focus for analysts. The functions of non-processed and processed medicinal herbs are greatly different, so controlling the processing procedure is highly important for guarantee of the curative effect. Almost, the conventional criteria of processing are based on personal sensory experience.

[Identification of categories of Radix Rehmannia by IR spectroscopy and compare software].

Objective: To identify the categories of Radix Rehmannia between the wild and the planting, different stored time, (gained in 2000,2002) , trueborn place (Henan) and no-trueborn places.

Methods: FTIR combined compare software, and the data was dealt with the means of normalization in computer.

Result: The wild and the planting have evident difference.

[The correlation between 2D-IR and HPLC in dried Rehmannia glutinosa processed by different processing techniques].

Objective: To establish one easier and higher efficient method of evaluating the quality of dried Rehmanwa glutinosa processed by different processing techniques in different producing areas.

Method: Studies on the correlations between 2D-IR and HPLC in dried R. glutinosa processed by different processing techniques.