Activated human Orai1 channel in lipid biolayer may exist as a pentamer.

The human Orai1 (hOrai1) channel plays a crucial role in extracellular Ca influx and has emerged as an attractive drug target for various diseases. However, the activated structure of the hOrai1 channel assembly within a lipid bilayer remains unknown. In this study, we expressed and purified the hOrai1 channel covalently linked to two SOAR tandems (HOSS).

Mechanism and efficiency of contaminant reduction by hydrated electron in the sulfite/iodide/UV process.

Advanced reduction by the extremely strong reducing species, hydrated electron (e), is a promising and viable approach to eliminate a wide variety of persistent and toxic contaminants. In this study, we proposed a sulfite/iodide/UV process, which offered efficient production of e for contaminant reduction. Using monochloroacetic acid (MCAA) as a simple e probe, the availability of e was assessed, and the mechanism involving the roles of S(IV) and iodide in the process was elucidated.

Synergistic photosensitized removal of Cr(VI) and Rhodamine B dye on amorphous TiO2 under visible light irradiation.

Amorphous TiO(2) (Am-TiO(2)) was prepared at room temperature by hydrolysis of Ti(OBu)(4) in water without addition of strong acids or organic solvents. Results from XRD and TEM revealed that the as-prepared Am-TiO(2) was composed of amorphous structure. For the simultaneous photosensitized removal of Cr(VI) and zwitterionic Rhodamine B (RhB) dye, Am-TiO(2) exhibited more significant synergistic effect than commercial P25-TiO(2).