Publications by authors named "Keenan Pituch"

Introduction: To examine whether within-person changes in total, regional and organ fat were associated with within-person changes in type 2 diabetes (T2D)-related biomarkers following interventions.

Methods: A secondary analysis from a randomised trial among Latino youth (30 males, 25 females) aged 12-16 years with obesity. The study sample combined participants randomised to either lifestyle intervention (N = 39) or usual care (N = 16).

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  • * The study will follow 300 participants with chronic low back pain, assessing factors like sleep disturbances and pain, using various methods over 12 months to identify their impact on developing multiple COPCs.
  • * The research aims to analyze how sleep and circadian rhythm issues relate to pain intensity, psychological distress, and the spread of pain across the body, potentially guiding future treatment and prevention approaches for these conditions.
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Problem, Research Strategy, and Findings: Low physical activity (PA) and Type 2 diabetes are associated with cognitive aging and Alzheimer's disease, but the evidence is inconsistent and particularly limited by ethnicity. The purpose of this study was to examine the relationships of PA and Type 2 diabetes with cognition in Mexican Americans and non-Hispanic Whites. The study was a cross-sectional analysis of the Health and Aging Brain Study-Health Disparities (n = 1,982-2,000 after removing outliers).

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  • The study aimed to explore how the COVID-19 pandemic affected infant sleep by looking at family distress, parental insomnia, and infants' negative emotions.
  • A total of 70 parents with infants under one year old participated, providing data through various surveys assessing pandemic impact and sleep quality.
  • Findings indicated that increased family distress related to the pandemic negatively impacted infant sleep, primarily through heightened negative emotions in infants, highlighting the need to focus on family well-being during crises.
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Objective: To examine the associations of cardiorespiratory fitness with executive function, episodic memory, and global cognition and sex differences in these associations in community-dwelling older adults with amnestic mild cognitive impairment.

Design: A cross-sectional study using baseline data from the aerobic exercise and cognitive training (ACT) trial.

Setting: The ACT trial conducted exercise testing in an exercise laboratory and data collections in a research facility.

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Background: The number of older adults in the U.S. living with ADRD is projected to increase dramatically by 2060.

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Objectives: To identify subgroups of patients with distinct chemotherapy-induced vomiting (CIV) profiles; determine how these subgroups differ on several demographic, clinical, and symptom characteristics; and evaluate factors associated with chemotherapy-induced nausea and CIV profiles.

Sample & Setting: Adult patients (N = 1,338) receiving cancer chemotherapy.

Methods & Variables: Data were collected on demographic, clinical, and symptom characteristics.

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  • Alzheimer's disease (AD) disproportionately affects Latinos, particularly Mexican Americans, potentially due to the link with type 2 diabetes (T2D) which is a known risk factor for AD.
  • This study analyzed health data from the Health and Aging Brain Study: Health Disparities (HABS-HD) to compare associations between T2D and Alzheimer's biomarkers in Mexican Americans versus non-Hispanic Whites.
  • Results indicated significant differences in blood glucose, HbA1c levels, T2D diagnosis rates, and various Alzheimer's biomarkers, with HbA1c showing a positive association with neurofilament light (NfL) levels in Mexican Americans, unlike in non-Hispanic Whites.
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To examine the extent to which older adults' perceived balance, a balance performance test, and fear of falling (FOF) were associated with falls in the last month. The Health Belief Model served as the theoretical framework. A retrospective, cross-sectional, secondary analysis using data from the National Health and Aging Trends Study was conducted ( = 7499).

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Background And Objectives: The primary aim of this Stage IB randomized controlled trial (RCT) was to test the preliminary effects of a dual-task exergaming telerehabilitation intervention on cognition and aerobic fitness, compared to aerobic exercise (AEx) only and attention control (stretching) in older adults with subjective cognitive decline.

Research Design And Methods: This RCT randomized 39 participants on a 2:1:1 allocation ratio to supervised exergame (n = 20), AEx (n = 11), and stretching (n = 8) for 12 weeks. The dual-task exergaming was concurrent moderate-intensity cycling and BrainFitRx cognitive telerehabilitation.

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Background: Latent inhibition occurs when exposure to a stimulus prior its direct associative conditioning impairs learning. Results from naturalistic studies suggest that latent inhibition disrupts the learning of dental fear from aversive associative conditioning and thereby reduces the development of dental phobia. Although theory suggests latent inhibition occurs because pre-exposure changes the expected relevance and attention directed to the pre-exposed stimulus, evidence supporting these mechanisms in humans is limited.

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  • The study investigates how family financial stress and individual factors like food insecurity and race affect mental health in Puerto Rican adolescents during the COVID-19 pandemic.
  • A sample of 119 adolescents, aged 13 to 17, was surveyed to explore the link between family financial stress and psychological distress, considering the moderating effects of family violence, food insecurity, and demographics.
  • Results indicate that food insecurity contributes to psychological distress, and racial identity influences the impact of family financial stress on mental health, with significant effects observed primarily in racial minority participants.
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Aims: To examine how perceived balance problems are associated with self-reported falls in the past month after controlling for known correlates of falls among older adults.

Background: Approximately 30% of adults age 65 and older fall each year. Most accidental falls are preventable, and older adults' engagement in fall prevention is imperative.

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Objectives: To evaluate differences in the severity of global, cancer-specific, and cumulative life stress, resilience, and common neuropsychological symptoms among four subgroups of patients with distinct chemotherapy-induced nausea (CIN) profiles.

Sample & Setting: Adult patients with cancer (N = 1,343) receiving chemotherapy.

Methods & Variables: Patients completed stress, resilience, and neuropsychological symptom severity measures.

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  • The study examines how the COVID-19 pandemic affects nurses, particularly regarding compassion fatigue (CF) and compassion satisfaction (CS), which can influence their job performance and well-being.
  • Data from nurses in the U.S., Japan, and South Korea showed that higher resilience leads to lower burnout and secondary traumatic stress, while higher intention to leave the profession correlates with increased burnout and stress.
  • Recommendations include enhancing organizational support, providing proper personal protective equipment (PPE), and developing resilience programs to improve nurses' mental health during crises.
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  • Dental anxiety often stems from direct fear conditioning, but exposure to dental stimuli beforehand may reduce this fear through a phenomenon called latent inhibition, which is still not well understood.
  • This study will enroll healthy volunteers aged 6 to 35 to investigate how pre-exposure to dental stimuli affects fear responses in a controlled virtual reality setting while measuring pain sensitivity.
  • The goal is to identify the mechanisms behind reduced fear acquisition and retention to improve dental phobia prevention strategies, ultimately enhancing both dental and overall health outcomes for individuals.
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Background: Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV can infect both females and males, and it can cause many cancers, including anal, cervical, vaginal, vulvar, and penile cancers. HPV vaccination rates are lower than vaccination rates within other national vaccination programs, despite its importance.

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Touch associated with sleep (; reported physical contact during or shortly before/after sleep) is underexplored as a distinct contributor to affect regulatory processes associated with adult sleep. Given the affect-regulating effects of interpersonal touch, we theorized that among healthy co-sleeping adults, sleep-touch would add to sleep-related effects on affective "resetting," resulting in the experience of calmer, more regulated states. We studied 210 married heterosexual couples (aged 20-67 years, 79% non-Hispanic white, 13% Latinx) assigned 14 days of twice-daily (morning/evening) sleep/mood diaries.

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  • * A study with 492 participants used latent profile analysis to categorize different levels of DRA based on factors like self-perceived risk and preparedness for future care.
  • * Four distinct profiles emerged, revealing that age and psychological functioning affect one's anxiety about dementia, with younger individuals showing the least anxiety and preparedness while older adults exhibited the most.
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Background: Unrelieved chemotherapy-induced nausea (CIN) occurs 48% of patients undergoing chemotherapy and is one of the most debilitating symptoms that patients report.

Objective: The aims of this study were to identify subgroups of patients with distinct CIN profiles and determine how these subgroups differed on demographic and clinical characteristics; severity, frequency, and distress of CIN; and the co-occurrence of common gastrointestinal symptoms.

Methods: Patients (n = 1343) completed demographic questionnaire and Memorial Symptom Assessment Scale 6 times over 2 cycles of chemotherapy.

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  • Chronic conditions need ongoing care, and the COVID-19 pandemic may have disrupted this access, particularly for Americans aged 50 and older.
  • A survey conducted during the pandemic revealed that individuals with an established primary care provider were significantly more likely to access healthcare and medications.
  • Factors such as age, income, and caregiving responsibilities influenced healthcare access, with older individuals and those with higher incomes having better access, while those with caregiving duties and social isolation faced challenges.
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Cultural stereotypes that equate aging with decreased competence and increased forgetfulness have persisted for decades. Stereotype threat (ST) refers to the psychological discomfort people experience when confronted by a negative, self-relevant stereotype in a situation where their behavior could be construed as confirming that belief. The purpose of this study was to examine the relationships of ST on memory performance in older adults over 24 months.

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Objectives: To describe changes in sleep patterns during the coronavirus disease 2019 (COVID-19) pandemic, develop profiles according to these patterns, and assess sociodemographic, economic, COVID-19 related, and sleep and mental health factors associated with these profiles.

Design, Setting, And Participants: A 25-minute online survey was distributed worldwide through social media from 5/21/2020 to 7/1/2020.

Measurements: Participants reported sociodemographic/economic information, the impact of the pandemic on major life domains, insomnia and depressive symptoms, and changes in sleep midpoint, time-in-bed, total sleep time (TST), sleep efficiency (SE), and nightmare and nap frequency from prior to during the pandemic.

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Purpose: In this secondary analysis we tested whether 12 h of Senior WISE (Wisdom Is Simply Exploration) memory or health training with older adults would produce better outcomes by gender in perceptions of anxiety and bodily pain and whether the effects of the Senior WISE training on pain were mediated by anxiety.

Design: An implemented Phase III randomized clinical trial with follow up for 24 months in Central Texas. The sample was mostly female (79%), 71% Caucasian, 17% Hispanic, and 12% African American with an average age of 75 and 13 years of education.

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